Matrougui, Khalid

Matrougui, Khalid
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matrouk@evms.edu

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selected publications

2019

Treg cells depletion is a mechanism that drives microvascular dysfunction in mice with established hypertension. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1865:403-412.
Full Text via DOI: 10.1016/j.bbadis.2018.10.031 PMID: 30414897
2019

Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1865:206-217.
Full Text via DOI: 10.1016/j.bbadis.2018.08.017 PMID: 30463689
2018

Essential role for EGFR tyrosine kinase and ER stress in myocardial infarction in type 2 diabetes. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 470:471-480.
Full Text via DOI: 10.1007/s00424-017-2097-5 PMID: 29288332
2018

Essential role for smooth muscle cell stromal interaction molecule-1 in myocardial infarction. JOURNAL OF HYPERTENSION. 36:377-386.
Full Text via DOI: 10.1097/HJH.0000000000001518 PMID: 29611835
2017

Essential Role of IL-12 in Angiogenesis in Type 2 Diabetes. AMERICAN JOURNAL OF PATHOLOGY. 187:2590-2601.
Full Text via DOI: 10.1016/j.ajPath.2017.07.021 PMID: 28837799
2017

Essential role for interleukin-12 in microvascular endothelial dysfunction in type 2 diabetes. FASEB JOURNAL.
2017

Interleukin-12 Disruption Protects Myocardium from Ischemia-Reperfusion Injury in Type 2 Diabetic Mice. FASEB JOURNAL.
2017

The Unraveling Truth About IRE1 and MicroRNAs in Diabetes. DIABETES. 66:23-24.
Full Text via DOI: 10.2337/dbi16-0058 PMID: 27999104
2016

Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function. JOURNAL OF BIOLOGICAL CHEMISTRY. 291:22894-22912.
Full Text via DOI: 10.1074/jbc.M116.756114 PMID: 27624938
2016

Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 36:1900-1909.
Full Text via DOI: 10.1161/ATVBAHA.116.307869 PMID: 27470514
2016

Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase and Endoplasmic Reticulum Stress Protects Myocardial from Ischemia Reperfusion Injury in Type 2 Diabetic Mice. FASEB JOURNAL.
2016

Stromal Interaction Molecule 1 Disruption Protects Myocardial from Ischemia - Reperfusion Injury. FASEB JOURNAL.
2015

Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 1853:2404-2410.
Full Text via DOI: 10.1016/j.bbamcr.2015.05.032 PMID: 26036345
2015

Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 467:2193-2218.
Full Text via DOI: 10.1007/s00424-014-1674-0 PMID: 25537398
2015

Differential role for stromal interacting molecule 1 in the regulation of vascular function. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 467:1195-1202.
Full Text via DOI: 10.1007/s00424-014-1556-5 PMID: 24965067
2015

A novel role of Three Prime Repair Exonuclease 1 (TREX1) in microvascular function and hypertension. FASEB JOURNAL.
2015

Enhanced p47(phox) NADPH sub-unit expression impairs conductance and resistance vascular function in obese mice. FASEB JOURNAL.
2015

Role of endoplasmic reticulum stress and thrombosis in type 2 diabetes-induced vascular dysfunction. FASEB JOURNAL.
2015

Leukotriene-C-4 Synthase, a Critical Enzyme in the Activation of Store-independent Orai1/Orai3 Channels, Is Required for Neointimal Hyperplasia. JOURNAL OF BIOLOGICAL CHEMISTRY. 290:5015-5027.
Full Text via DOI: 10.1074/jbc.M114.625822 PMID: 25540197
2015

Nuclear factor kappa B inhibition improves conductance artery function in type 2 diabetic mice. DIABETES-METABOLISM RESEARCH AND REVIEWS. 31:39-49.
Full Text via DOI: 10.1002/dmrr.2542 PMID: 24652705
2014

Can the NK Family of Osteoblast Homeodomain Transcription Factors Signaling Be a Magic Bullet to Reverse Calcification-Induced Vasculopathy in Diabetes?. DIABETES. 4011-4012.
Full Text via DOI: 10.2337/db14-1366 PMID: 25414018
2014

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 1843:1063-1075.
Full Text via DOI: 10.1016/j.bbamcr.2014.02.009 PMID: 24576409
2014

Enhanced p22(phox) expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 306:H972-H980.
Full Text via DOI: 10.1152/ajpheart.00872.2013 PMID: 24486509
2014

Omental fat from obese and obese diabetic patients dys-regulates vascular function by NF-kappa B, PARP-1 and interleukin 12-dependent mechanism. FASEB JOURNAL.
2014

Complex role of STIM1 in the activation of store-independent Orai1/3 channels. JOURNAL OF GENERAL PHYSIOLOGY. 143:345-359.
Full Text via DOI: 10.1085/jgp.201311084 PMID: 24567509
2013

CD(4)(+)CD(25)(+)Foxp3 regulatory T cells and vascular dysfunction in hypertension. JOURNAL OF HYPERTENSION. 31:1939-1943.
Full Text via DOI: 10.1097/HJH.0b013e328362feb7 PMID: 23881298
2013

Mechanisms of STIM1 Activation of Store-Independent Leukotriene C-4-Regulated Ca2+ Channels. MOLECULAR AND CELLULAR BIOLOGY. 33:3715-3723.
Full Text via DOI: 10.1128/MCB.00554-13 PMID: 23878392
2013

STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 465:1249-1260.
Full Text via DOI: 10.1007/s00424-013-1254-8 PMID: 23515871
2013

Enhanced NF-kappa B Activity Impairs Vascular Function Through PARP-1-, SP-1-, and COX-2-Dependent Mechanisms in Type 2 Diabetes. DIABETES. 62:2078-2087.
Full Text via DOI: 10.2337/db12-1374 PMID: 23349490
2013

Store-Independent Orai1/3 Channels Activated by Intracrine LeukotrieneC(4) Role in Neointimal Hyperplasia. CIRCULATION RESEARCH. 112:1013-U104.
Full Text via DOI: 10.1161/CIRCRESAHA.111.300220 PMID: 23349245

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Khalid Matrougui

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