Perspectives on Triple-Negative Breast Cancer: Current Treatment Strategies, Unmet Needs, and Potential Targets for Future Therapies Review

Open Access

author list

  • Gupta, Gagan K.; Collier, Amber L.; Lee, Dasom; Hoefer, Richard A.; Zheleva, Vasilena; Siewertsz van Reesema, Lauren L.; Tang-Tan, Angela M.; Guye, Mary L.; Chang, David Z.; Winston, Janet S.; Samli, Billur; Jansen, Rick J.; Petricoin, Emanuel F.; Goetz, Matthew P.; Bear, Harry D.; Tang, Amy H.

publication date

  • September 1, 2020


published in



  • Cytoxan
  • EGFR
  • K-RAS
  • SIAH signaling pathway
  • and Taxotere)
  • chemo-resistance
  • clinical diagnostics
  • concurrent ACT regimen (Adriamycin
  • improved patient survival
  • neoadjuvant chemotherapy (NACT)
  • pathologic incomplete responders (pIR)
  • prognostics
  • residual cancer burden (RCB)
  • sequential ACT regimen (AC-T)
  • triple-negative breast cancer (TNBC)
  • tumor recurrence
  • tumor-driving signaling pathways in TNBC


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