Persistent EGFR/K-RAS/SIAH pathway activation drives chemo-resistance and early tumor relapse in triple-negative breast cancer Review

publication date

  • January 1, 2022

webpage

published in

keywords

  • EGFR/K-RAS/SIAH pathway activation in TNBC
  • Triple-negative breast cancer ( TNBC)
  • and treatment optimization
  • chemo-resistance
  • detection of chemo-resistance
  • neoadjuvant chemotherapy prognosis
  • patient risk stratification
  • precision quantification of therapy efficacy
  • seven in absentia (SINA) and human homologs of SINA ( SIAH) E3 ligase
  • ubiquitin-mediated proteolysis

start page

  • 691

end page

  • 702

volume

  • 5

issue

  • 3