Chandra, Neelima

Chandra, Neelima
Close

Contact Info

chandrn@evms.edu

selected publications

2022

Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 226:225.e1-225.e15.
Full Text via DOI: 10.1016/j.ajog.2021.09.018
2019

The Effect of Hormonal Contraception on Cervicovaginal Mucosal End Points Associated with HIV Acquisition. AIDS RESEARCH AND HUMAN RETROVIRUSES. 35:1-12.
Full Text via DOI: 10.1089/aid.2018.0298 PMID: 30997816
2018

Effect of Hormonal Contraception on Pharmacokinetics of Vaginal Tenofovir: Increased Tenofovir Diphosphate in Depot Medroxyprogesterone Acetate Users. AIDS RESEARCH AND HUMAN RETROVIRUSES. 342-342.
2018

Use of contraceptive depot medroxyprogesterone acetate is associated with impaired cervicovaginal mucosal integrity. JOURNAL OF CLINICAL INVESTIGATION. 128:4622-4638.
Full Text via DOI: 10.1172/JCI120583 PMID: 30222141
2018

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women. PLOS ONE. 13.
Full Text via DOI: 10.1371/journal.pone.0199778 PMID: 29953547
2018

Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 78:82-92.
Full Text via DOI: 10.1097/QAI.0000000000001648 PMID: 29424790
2017

Comparison of Mucosal Markers of Human Immunodeficiency Virus Susceptibility in Healthy Premenopausal Versus Postmenopausal Women. AIDS RESEARCH AND HUMAN RETROVIRUSES. 33:807-819.
Full Text via DOI: 10.1089/aid.2016.0320 PMID: 28398069
2016

Epithelial Barrier Alteration and Increased HIV Target Cells Coexist in Inflamed Human Cervices: A Biological Pathway to Enhanced HIV Susceptibility?. AIDS RESEARCH AND HUMAN RETROVIRUSES. 318-318.
2016

Long-acting Intrauterine System Delivers Integrase Inhibitor Throughout the Reproductive Tract of Rabbits and Macaques. AIDS RESEARCH AND HUMAN RETROVIRUSES. 227-227.
2016

The Role of Vitamin D on Genital Mucosal Immunity and Markers of HIV Susceptibility in Women. AIDS RESEARCH AND HUMAN RETROVIRUSES. 320-320.
2016

Use of Injectable Depot Medroxyprogesterone Acetate (DMPA) Downregulates Vaginal Epithelial Barrier Genes - Similarly to Mucosal Inflammation. AIDS RESEARCH AND HUMAN RETROVIRUSES. 46-46.
2016

Comparison of Follicular and Luteal Phase Mucosal Markers of HIV Susceptibility in Healthy Women. AIDS RESEARCH AND HUMAN RETROVIRUSES. 32:547-560.
Full Text via DOI: 10.1089/aid.2015.0264 PMID: 26750085
2015

Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity. AIDS RESEARCH AND HUMAN RETROVIRUSES. 31:1139-1152.
Full Text via DOI: 10.1089/aid.2015.0006 PMID: 26204200
2015

A quantitative multiplex nuclease protection assay reveals immunotoxicity gene expression profiles in the rabbit model for vaginal drug safety evaluation. TOXICOLOGY AND APPLIED PHARMACOLOGY. 285:198-206.
Full Text via DOI: 10.1016/j.taap.2015.02.017 PMID: 25818602
2014

Effect of Bacterial Vaginosis on Markers of Genital Tract Inflammation and Mucosal Immunity: Mechanisms for Susceptibility to HIV Infection. AIDS RESEARCH AND HUMAN RETROVIRUSES. A30-A30.
2014

Gene Expression Analysis of Human Vaginal Mucosal Response to Pro-inflammatory Stimuli - Identification of Biomarkers of Vaginal Inflammation. AIDS RESEARCH AND HUMAN RETROVIRUSES. A239-A239.
2014

Mucosal Susceptibility to HIV-1 and Tenofovir Protection in Explanted Cervicovaginal Tissues from Postmenopausal Compared to Premenopausal Women. AIDS RESEARCH AND HUMAN RETROVIRUSES. A264-A265.
2014

COX-2, NF-kappa B, and IL-8 Expression in the Placenta in Severe Preeclampsia. REPRODUCTIVE SCIENCES. 190A-190A.
2013

Toward Early Safety Alert Endpoints: Exploring Biomarkers Suggestive of Microbicide Failure. AIDS RESEARCH AND HUMAN RETROVIRUSES. 29:1475-1486.
Full Text via DOI: 10.1089/aid.2012.0345 PMID: 23885658
2013

Depot Medroxyprogesterone Acetate Increases Immune Cell Numbers and Activation Markers in Human Vaginal Mucosal Tissues. AIDS RESEARCH AND HUMAN RETROVIRUSES. 29:592-601.
Full Text via DOI: 10.1089/aid.2012.0271 PMID: 23189932
2013

Seminal Plasma Induces Prostaglandin-Endoperoxide Synthase (PTGS) 2 Expression in Immortalized Human Vaginal Cells: Involvement of Semen Prostaglandin E2 in PTGS2 Upregulation. BIOLOGY OF REPRODUCTION. 88.
Full Text via DOI: 10.1095/biolreprod.112.101956 PMID: 23153564
2012

A 90-Day Tenofovir Reservoir Intravaginal Ring for Mucosal HIV Prophylaxis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 56:6272-6283.
Full Text via DOI: 10.1128/AAC.01431-12 PMID: 23006751
2012

Impact of depot medroxyprogesterone (DMPA) on human vaginal leukocytes and HIV-1 target cells. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 24-24.
2012

Induction of Cyclooxygenase (COX)-2 in Human Vaginal Epithelial Cells in Response to TLR ligands and TNF-a. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 67:482-490.
Full Text via DOI: 10.1111/j.1600-0897.2011.01099.x PMID: 22235849
2008

Six-Day Randomized Safety Trial of Intravaginal Lime Juice. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 49:243-250.
2007

Biomarkers of leukocyte traffic and activation in the vaginal mucosa. BIOMARKERS. 12:608-622.
Full Text via DOI: 10.1080/13547500701600670 PMID: 17852080

full name

Neelima Chandra

visualizations

Recent publications and grants in Researchers@EVMS

Co-author Network

research areas