Galkin, Vitold E.
- Associate Professor, Physiological Sciences
Contact Info
Publications
selected publications
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2021Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin. JOURNAL OF MOLECULAR BIOLOGY. 433.Full Text via DOI: 10.1016/j.jmb.2021.167178 PMID: 34329643
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2021The structure of the native cardiac thin filament at systolic Ca2+ levels. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 118.Full Text via DOI: 10.1073/pnas.2024288118 PMID: 33753506
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2021High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex. STRUCTURE. 29:50-+.Full Text via DOI: 10.1016/j.str.2020.09.013 PMID: 33065066
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2021Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.. CHEMICAL SCIENCE. 12:7308-7323.Full Text via DOI: 10.1039/d1sc01886h PMID: 34163821
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2019
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2019Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics. MOLECULAR BIOLOGY OF THE CELL. 30:268-281.Full Text via DOI: 10.1091/mbc.E18-06-0406 PMID: 30462572
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2019Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics.. MOLECULAR BIOLOGY OF THE CELL. 30:268-281.Full Text via DOI: 10.1091/mbc.e18-06-0406 PMID: 30462572
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2018N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. STRUCTURE. 26:1604-+.Full Text via DOI: 10.1016/j.str.2018.08.007 PMID: 30270174
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2018N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. STRUCTURE. 26:1604-+.Full Text via DOI: 10.1016/j.str.2018.08.007 PMID: 30270174
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2018Accurate flexible refinement of atomic models against medium-resolution cryo-EM maps using damped dynamics. BMC STRUCTURAL BIOLOGY. 18.Full Text via DOI: 10.1186/s12900-018-0089-0 PMID: 30219048
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2018Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate. MOLECULAR CANCER RESEARCH. 16:669-681.Full Text via DOI: 10.1158/1541-7786.MCR-17-0321 PMID: 29330297
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2018
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2018CA(2+)-Induced Movement of Tropomyosin on Native Cardiac Thin Filaments Revealed by Cryoelectron Microscopy. BIOPHYSICAL JOURNAL. 138A-138A.
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2018Accurate flexible refinement of atomic models against medium-resolution cryo-EM maps using damped dynamics.. BMC STRUCTURAL BIOLOGY. 18:12.Full Text via DOI: 10.1186/s12900-018-0089-0 PMID: 30219048
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2017Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii. JOURNAL OF BIOLOGICAL CHEMISTRY. 292:10899-10911.Full Text via DOI: 10.1074/jbc.M116.762229 PMID: 28476887
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2017Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 114:6782-6787.Full Text via DOI: 10.1073/pnas.1700868114 PMID: 28607071
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2017Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis. JOURNAL OF MOLECULAR BIOLOGY. 429:715-731.Full Text via DOI: 10.1016/j.jmb.2017.01.020 PMID: 28147230
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2017Ca<sup>2+</sup>-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 114:6782-6787.Full Text via DOI: 10.1073/pnas.1700868114 PMID: 28607071
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2017Filaments and fingers: Novel structural aspects of the single septin from <i>Chlamydomonas reinhardtii</i>.. The Journal of biological chemistry. 292:10899-10911.Full Text via DOI: 10.1074/jbc.m116.762229 PMID: 28476887
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2017Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis.. JOURNAL OF MOLECULAR BIOLOGY. 429:715-731.Full Text via DOI: 10.1016/j.jmb.2017.01.020 PMID: 28147230
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2016C0 and C1 N-Terminal Ig-Domains of Myosin Binding Protein-C Exert Different Effects on thin Filament Activation. BIOPHYSICAL JOURNAL. 125A-125A.
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2016C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113:1558-1563.Full Text via DOI: 10.1073/pnas.1518891113 PMID: 26831109
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2016Multimodal and polymorphic interactions between anillin and actin: their implications for cytokinesis.. MOLECULAR BIOLOGY OF THE CELL.
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2015Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity. JOURNAL OF MOLECULAR BIOLOGY. 427:3273-3284.Full Text via DOI: 10.1016/j.jmb.2015.07.026 PMID: 26297986
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2015Cryo-EM of One State of F-Actin Yields a New Atomic Filament Model. BIOPHYSICAL JOURNAL. 299A-299A.
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2015Near-Atomic Resolution for One State of F-Actin. STRUCTURE. 23:173-182.Full Text via DOI: 10.1016/j.str.2014.11.006 PMID: 25533486
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2015Near-atomic resolution for one state of F-actin.. STRUCTURE. 23:173-182.Full Text via DOI: 10.1016/j.str.2014.11.006 PMID: 25533486
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2015Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity.. JOURNAL OF MOLECULAR BIOLOGY. 427:3273-3284.Full Text via DOI: 10.1016/j.jmb.2015.07.026 PMID: 26297986
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2014Septin 9 is an actin binding protein which bundles F-actin through a unique N-terminal domain.. MOLECULAR BIOLOGY OF THE CELL.
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2014
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2014Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility. JOURNAL OF CELL BIOLOGY. 207:225-235.Full Text via DOI: 10.1083/jcb.201405050 PMID: 25349260
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2014Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins. INTERNATIONAL JOURNAL FOR PARASITOLOGY. 44:523-531.Full Text via DOI: 10.1016/j.ijpara.2014.03.010 PMID: 24768753
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2014Mapping Anillin-Actin Interactions. BIOPHYSICAL JOURNAL. 571A-571A.
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2014Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties. STRUCTURE. 22:697-706.Full Text via DOI: 10.1016/j.str.2014.03.002 PMID: 24685146
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2014Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.. INTERNATIONAL JOURNAL FOR PARASITOLOGY. 44:523-31.Full Text via DOI: 10.1016/j.ijpara.2014.03.010 PMID: 24768753
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2014Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility.. JOURNAL OF CELL BIOLOGY. 207:225-35.Full Text via DOI: 10.1083/jcb.201405050 PMID: 25349260
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2013Focal adhesion maturation requires septin-mediated assembly of actin stress fibers. MOLECULAR BIOLOGY OF THE CELL.
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2013Mapping anillin-actin interactions. MOLECULAR BIOLOGY OF THE CELL.
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2013The Structure of the CS1 Pilus of Enterotoxigenic Escherichia coli Reveals Structural Polymorphism. JOURNAL OF BACTERIOLOGY. 195:1360-1370.Full Text via DOI: 10.1128/JB.01989-12 PMID: 23175654
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2012Actin Filaments as Tension Sensors. CURRENT BIOLOGY. R96-R101.Full Text via DOI: 10.1016/j.cub.2011.12.010 PMID: 22321312
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2012Are ParM Filaments Polar or Bipolar?. JOURNAL OF MOLECULAR BIOLOGY. 423:482-485.Full Text via DOI: 10.1016/j.jmb.2012.08.006 PMID: 22922064
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2011Crystal Structure of the Phage T4 Recombinase UvsX and Its Functional Interaction with the T4 SF2 Helicase UvsW. JOURNAL OF MOLECULAR BIOLOGY. 405:65-76.Full Text via DOI: 10.1016/j.jmb.2010.10.004 PMID: 21035462
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2011Remodeling of actin filaments by ADF/cofilin proteins. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 108:20568-20572.Full Text via DOI: 10.1073/pnas.1110109108 PMID: 22158895
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2011The N-Terminal Domains of Myosin Binding Protein C Can Bind Polymorphically to F-Actin. JOURNAL OF MOLECULAR BIOLOGY. 412:379-386.Full Text via DOI: 10.1016/j.jmb.2011.07.056 PMID: 21821050
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2011Two Modes of Binding of DinI to RecA Filament Provide a New Insight into the Regulation of SOS Response by DinI Protein. JOURNAL OF MOLECULAR BIOLOGY. 408:815-824.Full Text via DOI: 10.1016/j.jmb.2011.03.046 PMID: 21458462
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2010Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 17:1255-+.Full Text via DOI: 10.1038/nsmb.1916 PMID: 20871616
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2010Mapping of Drebrin Binding Site on F-Actin. JOURNAL OF MOLECULAR BIOLOGY. 398:542-554.Full Text via DOI: 10.1016/j.jmb.2010.03.039 PMID: 20347847
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2010Opening of tandem calponin homology domains regulates their affinity for F-actin. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 17:614-616.Full Text via DOI: 10.1038/nsmb.1789 PMID: 20383143
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2010ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107:4590-4595.Full Text via DOI: 10.1073/pnas.0913060107 PMID: 20176965
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2010Structural polymorphism in F-actin. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 17:1318-U169.Full Text via DOI: 10.1038/nsmb.1930 PMID: 20935633
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2010The Structure of the Salmonella typhimurium Type III Secretion System Needle Shows Divergence from the Flagellar System. JOURNAL OF MOLECULAR BIOLOGY. 396:1392-1397.Full Text via DOI: 10.1016/j.jmb.2010.01.001 PMID: 20060835
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full name
- Vitold E. Galkin