Siraj, Elias S.
- Chief Of Endocrine Division, Director Of Strelitz Diabetes Center, Internal Medicine
Overview
overview
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Dr Siraj is currently Professor and Chief of Division of Endocrine & Metabolic Disorders and Associate Dean for Clinical Research at Eastern Virginia Medical School (EVMS), Norfolk, VA. He is also David L. Bernd Distinguished Chair for Cardiovascular and Diabetes Program & Director of Strelitz Diabetes Center. He has also been recently appointed at the Associate Dean for Clinical Research of EVMS. Dr. Siraj started as a Faculty first at the Cleveland Clinic and later moved to Temple University in Philadelphia where for many years he carried various leadership roles including Director of Diabetes Program and Director of Endocrine Fellowship Program.
After receiving his medical degree as the best student of the year from Gondar Medical College of the Addis Ababa University, Ethiopia, Dr. Siraj received residency and research training at the University of Leipzig, in Germany. In the US, he did his residency and fellowship training at the Cleveland Clinic.
Dr. Siraj is board-certified in endocrinology, diabetes and metabolism as well as in internal medicine, and is an active member of several professional organizations including the American Diabetes Association, Endocrine Society, American Association of Clinical Endocrinologists (AACE) and American College of Physicians. Some of the key leadership roles he played in the past include Board Member of the ABIM Endocrinology subsection, President of Philadelphia Endocrine Society and Council Member of the Association of Program Directors in Endocrinology, Diabetes & Metabolism (APDEM). A frequent national and international lecturer at professional meetings, he has published more than 100 original articles, abstracts and book chapters on the diagnosis and management of diabetes and endocrine problems. He serves as reviewer of prominent professional journals such as The Lancet Diabetes & Endocrinology, Journal of Clinical Endocrinology & Metabolism and is in the editorial board of many other journals. To be highlighted are his publications at prestigious journals such as New England Journal of Medicine, Lancet Diabetes & Endocrinology and his contribution to the text book of Rubin's Pathology.
Dr. Siraj is involved in research and trials involving diabetes, complications of diabetes, prevention of type 1 diabetes, diabetes in Ethiopia and post-transplant diabetes as well other areas of endocrinology. He has been an investigator in several multi center diabetes trials including the land mark ACCORD study. Over the next few years, Dr. Siraj's research will be focusing on diabetes and cardiovascular disease; outcomes research, health disparities and collaborative research projects with biopharmaceutical companies in the area of clinical diabetes.
Over the years, Dr. Siraj has been involved in Global Medicine activities and has been traveling to Ethiopia every year as a Visiting Professor, teaching residents, fellows and medical students as well as conducting collaborative clinical research projects. In collaboration with others, he was instrumental in successfully establishing the first Endocrine Fellowship training program in Ethiopia. By doing collaborative research in Ethiopia, he made significant contribution to our understanding of diabetes in Ethiopia. In addition, Dr Siraj has served in various leadership roles at "People to People", a US based NGO established by Ethiopian Physicians to support Ethiopian Healthcare and Medical Education. For his active role in Ethiopia, he received the prestigious Outstanding Service Award for the Promotion of Endocrine Health of an Underserved Population from the American Association of Clinical Endocrinology in 2014. In 2009, he also received Recognition Certificate from the President of the Federal Democratic Republic of Ethiopia, for his support of the healthcare system and medical education in Ethiopia.
Publications
selected publications
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2019Effect of Diabetes Mellitus on Complication Rates of Coronary Artery Bypass Grafting. AMERICAN JOURNAL OF CARDIOLOGY. 124:1389-1396.Full Text via DOI: 10.1016/j.amjcard.2019.07.053 PMID: 31481175
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2019Voluntary Adoption of an All In Match Policy in the Medical Specialties Matching Program: Advantages and Disadvantages.. Journal of graduate medical education. 378-381.Full Text via DOI: 10.4300/JGME-D-18-01090.1 PMID: 31440329
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2019Voluntary Adoption of an All In Match Policy in the Medical Specialties Matching Program: Advantages and Disadvantages. Journal of Graduate Medical Education. 378-381.Full Text via DOI: 10.4300/jgme-d-18-01090.1 PMID: 31440329
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2018Islet Cell Associated Autoantibodies and C-Peptide Levels in Patients with Diabetes and Symptoms of Gastroparesis. FRONTIERS IN ENDOCRINOLOGY. 9.Full Text via DOI: 10.3389/fendo.2018.00032 PMID: 29487566
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2018Glucose sensor-augmented continuous subcutaneous insulin infusion in patients with diabetic gastroparesis: An open-label pilot prospective study. PLOS ONE. 13.Full Text via DOI: 10.1371/journal.pone.0194759 PMID: 29652893
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2017Diabetes in sub-Saharan Africa: from clinical care to health policy. LANCET DIABETES & ENDOCRINOLOGY. 622-667.Full Text via DOI: 10.1016/S2213-8587(17)30181-X PMID: 28688818
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2017Diabetes in sub-Saharan Africa: from clinical care to health policy. LANCET DIABETES & ENDOCRINOLOGY. 622-667.Full Text via DOI: 10.1016/s2213-8587(17)30181-x PMID: 28688818
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2016Islet cell-associated autoantibodies in Ethiopians with diabetes mellitus. JOURNAL OF DIABETES AND ITS COMPLICATIONS. 30:1039-1042.Full Text via DOI: 10.1016/j.jdiacomp.2016.05.005 PMID: 27220543
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2016The impact of gastroparesis on diabetes control: Patient perceptions. JOURNAL OF DIABETES AND ITS COMPLICATIONS. 30:826-829.Full Text via DOI: 10.1016/j.jdiacomp.2016.03.025 PMID: 27166926
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2016Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response.. FRONTIERS IN GENETICS. 7:138.Full Text via DOI: 10.3389/fgene.2016.00138 PMID: 27775101
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2015Another Agent for Obesity - Will This Time Be Different?. NEW ENGLAND JOURNAL OF MEDICINE. 82-83.Full Text via DOI: 10.1056/NEJMe1506236 PMID: 26132945
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2015Insulin Dose and Cardiovascular Mortality in the ACCORD Trial. DIABETES CARE. 38:2000-2008.Full Text via DOI: 10.2337/dc15-0598 PMID: 26464212
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2015Liraglutide in Weight Management REPLY. NEW ENGLAND JOURNAL OF MEDICINE. 1780-1780.Full Text via DOI: 10.1056/NEJMc1509759 PMID: 26516641
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2015Another Agent for Obesity — Will This Time Be Different?. NEW ENGLAND JOURNAL OF MEDICINE. 82-83.Full Text via DOI: 10.1056/nejme1506236 PMID: 26132945
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2015Liraglutide in Weight Management. NEW ENGLAND JOURNAL OF MEDICINE. 1779-1782.Full Text via DOI: 10.1056/nejmc1509759 PMID: 26510031
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2015Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. AMERICAN JOURNAL OF HYPERTENSION. 28:995-1009.Full Text via DOI: 10.1093/ajh/hpu292 PMID: 25666468
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2013Determinants of Weight Gain in the Action to Control Cardiovascular Risk in Diabetes Trial. DIABETES CARE. 36:2162-2168.Full Text via DOI: 10.2337/dc12-1391 PMID: 23412077
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2012A Simple Screening Method for Individuals at Risk of Developing Type 1 Diabetes: Measurement of Islet Cell Autoantibodies (GADA, IA-2A, and IAA) on Dried Capillary Blood Spots Collected on Filter Paper. Hormone and Metabolic Research. 44:855-860.Full Text via DOI: 10.1055/s-0032-1316349 PMID: 22893260
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2011DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy. EPIGENETICS. 6:20-28.Full Text via DOI: 10.4161/epi.6.1.13362 PMID: 21150313
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2011Dietary Intake and Nutritional Deficiencies in Patients With Diabetic or Idiopathic Gastroparesis. Gastroenterology. 141:486-498.e7.Full Text via DOI: 10.1053/j.gastro.2011.04.045 PMID: 21684286
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2011Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes. NEW ENGLAND JOURNAL OF MEDICINE. 364:818-828.Full Text via DOI: 10.1056/nejmoa1006524 PMID: 21366473
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2011Similarities and Differences Between Diabetic and Idiopathic Gastroparesis. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 9:1056-1064.Full Text via DOI: 10.1016/j.cgh.2011.08.013 PMID: 21871247
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2010Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. LANCET. 376:419-430.Full Text via DOI: 10.1016/s0140-6736(10)60576-4 PMID: 20594588
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2010Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus. NEW ENGLAND JOURNAL OF MEDICINE. 1563-1574.Full Text via DOI: 10.1056/nejmoa1001282 PMID: 20648456
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2010Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus. NEW ENGLAND JOURNAL OF MEDICINE. 362:1575-1585.Full Text via DOI: 10.1056/nejmoa1001286 PMID: 20228401
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2010Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes. NEW ENGLAND JOURNAL OF MEDICINE. 363:233-244.Full Text via DOI: 10.1056/nejmoa1001288 PMID: 20587587
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2010Risk Factors and Outcomes Associated With Posttransplant Diabetes Mellitus in Kidney Transplant Recipients. TRANSPLANTATION PROCEEDINGS. 42:1685-1689.Full Text via DOI: 10.1016/j.transproceed.2009.12.062 PMID: 20620501
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2009Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials. Clinical Trials: Journal of the Society for Clinical Trials. 6:416-429.Full Text via DOI: 10.1177/1740774509344440 PMID: 19737845
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2008Effect of spironolactone therapy on albuminuria in patients with type 2 diabetes treated with angiotensin-converting enzyme inhibitors.. ENDOCRINE PRACTICE. 14:985-92.Full Text via DOI: 10.4158/ep.14.8.985 PMID: 19095597
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2008Effects of Intensive Glucose Lowering in Type 2 Diabetes. NEW ENGLAND JOURNAL OF MEDICINE. 358:2545-2559.Full Text via DOI: 10.1056/nejmoa0802743 PMID: 18539917
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2008Effects of Ramipril and Rosiglitazone on Cardiovascular and Renal Outcomes in People With Impaired Glucose Tolerance or Impaired Fasting Glucose: Results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. DIABETES CARE. 31:1007-1014.Full Text via DOI: 10.2337/dc07-1868 PMID: 18268075
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2008Effects of sulodexide in patients with type 2 diabetes and persistent albuminuria.. NEPHROLOGY DIALYSIS TRANSPLANTATION. 23:1946-54.Full Text via DOI: 10.1093/ndt/gfm893 PMID: 18089623
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2008Hypomagnesemia in Ethiopians with diabetes mellitus.. Ethnicity & disease. 18:147-51.PMID: 18507265
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2008Low levels of magnesium place diabetics at increased risk.. Ethnicity & disease. 238.PMID: 18509935
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2006Giant invasive pituitary prolactinoma with falsely low serum prolactin: the significance of 'hook effect'.. Journal of neuro-oncology. 79:41-3.Full Text via DOI: 10.1007/s11060-005-9108-7 PMID: 16598425
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2006Graves' disease discovered by angiography.. Thyroid : official journal of the American Thyroid Association. 703-703.Full Text via DOI: 10.1089/thy.2006.16.703 PMID: 16889497
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2006Inhaled human insulin: an inspiration for patients with diabetes mellitus?. CLEVELAND CLINIC JOURNAL OF MEDICINE. 73:569-578.Full Text via DOI: 10.3949/ccjm.73.6.569 PMID: 16784157
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2006Lipid and lipoprotein profiles in Ethiopian patients with diabetes mellitus.. METABOLISM-CLINICAL AND EXPERIMENTAL. 55:706-10.Full Text via DOI: 10.1016/j.metabol.2005.08.002 PMID: 16713427
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2006Metastatic malignant insulinoma in a patient with type 2 diabetes mellitus: case presentation and literature review.. ENDOCRINE PRACTICE. 12:411-6.Full Text via DOI: 10.4158/ep.12.4.411 PMID: 16901797
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2006Successful Treatment of Sulfonylurea-Induced Prolonged Hypoglycemia with use of Octreotide. ENDOCRINE PRACTICE. 12:635-640.Full Text via DOI: 10.4158/ep.12.6.635
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2005Restless legs syndrome associated with primary hyperparathyroidism.. SLEEP MEDICINE. 6:283-5.Full Text via DOI: 10.1016/j.sleep.2004.10.014 PMID: 15854861
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2003A diabetic woman with worsening heart failure, hunger, and tremor.. CLEVELAND CLINIC JOURNAL OF MEDICINE. 882-888.Full Text via DOI: 10.3949/ccjm.70.10.882 PMID: 14621233
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2003DEVELOPMENT OF DIABETES MELLITUS SEVERAL YEARS AFTER MANIFESTATION OF DIABETIC NEPHROPATHY: CASE REPORT AND REVIEW OF LITERATURE. ENDOCRINE PRACTICE. 9:301-306.Full Text via DOI: 10.4158/ep.9.4.301
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2003Is there a role for metformin or acarbose as a weight-loss agent in the absence of diabetes?. CLEVELAND CLINIC JOURNAL OF MEDICINE. 702-4.Full Text via DOI: 10.3949/ccjm.70.8.702 PMID: 12959396
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2003Raloxifene causing malabsorption of levothyroxine.. Archives of internal medicine. 163:1367-70.Full Text via DOI: 10.1001/archinte.163.11.1367 PMID: 12796075
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2002Basal and postglucagon C-peptide levels in Ethiopians with diabetes.. DIABETES CARE. 25:453-7.Full Text via DOI: 10.2337/diacare.25.3.453 PMID: 11874929
Research
research overview
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- Diabetes and cardiovascular outcomes
- Diabetic Neuropathy
- Diabetes and health disparities
- Diabetes and outcomes research
- Complications of diabetes
- Diabetes clinical trials
- Global aspects of diabetes with a focus on Africa
principal investigator on
projects
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Current Project
- Effect of GLP1 agonists on CV outcomes in patients with obesity (with or without diabetes)
- Regeneration of Epidermal Nerves in Human Diabetic Neuropathy
- SGLT2 inhibitors in heart failure (with our without diabetes)
- The Effects of Liraglutide on SUDOMOTOR Function and Inflammation in Type 2 Diabetes
- Topiramate as a Disease Altering Therapy for Cryptogenic Sensory Peripheral Neuropathy (CSPN)
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Past Project
Contact
preferred title
- Chief Of Endocrine Division, Director Of Strelitz Diabetes Center
full name
- Elias S. Siraj, MD
visualizations
Recent publications and grants in Researchers@EVMS
research areas
- Biochemistry & Molecular Biology
- Cardiovascular System & Cardiology
- Endocrinology & Metabolism
- Gastroenterology & Hepatology
- General & Internal Medicine
- Genetics & Heredity
- Immunology
- Neurosciences & Neurology
- Oncology
- Public, Environmental & Occupational Health
- Research & Experimental Medicine
- Science & Technology - Other Topics
- Surgery
- Transplantation
- Urology & Nephrology