Forgacs-Lonart, Eva

Forgacs-Lonart, Eva
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Positions

Associate Professor, Physiological Sciences

Contact Info

forgace@evms.edu

selected publications

2019

Human Beta-Cardiac Myosin Cardiomyopathy Mutations R712L and E497D Disrupt a Key Salt-Bridge in the Coupling Domain. BIOPHYSICAL JOURNAL. 264A-264A.
2018

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. STRUCTURE. 26:1604-+.
Full Text via DOI: 10.1016/j.str.2018.08.007 PMID: 30270174
2018

The shaker-1 mouse myosin VIIa deafness mutation results in a severely reduced rate of the ATP hydrolysis step. JOURNAL OF BIOLOGICAL CHEMISTRY. 293:819-829.
Full Text via DOI: 10.1074/jbc.M117.810119 PMID: 29167268
2017

Biochemical and Mechanical Properties of the S532P and R712L Cardiomyopathy Myosin Mutants. BIOPHYSICAL JOURNAL. 556A-557A.
2017

Kinetic Characterization of the Mitochondrial Transporter Human Myosin XIX. BIOPHYSICAL JOURNAL. 264A-264A.
2015

Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity. JOURNAL OF MOLECULAR BIOLOGY. 427:3273-3284.
Full Text via DOI: 10.1016/j.jmb.2015.07.026 PMID: 26297986
2015

Structural basis for drug-induced allosteric changes to human beta-cardiac myosin motor activity. NATURE COMMUNICATIONS. 6.
Full Text via DOI: 10.1038/ncomms8974 PMID: 26246073
2015

Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine beta-Cardiac Myosin. BIOCHEMISTRY. 54:1963-1975.
Full Text via DOI: 10.1021/bi5015166 PMID: 25680381
2013

Engineering of the Myosin Viia Nucleotide-Binding Pocket to Create Selective Sensitivity to N-6-Modified ADP Analogs. BIOPHYSICAL JOURNAL. 644A-644A.
2013

The Affect of Omecamtiv Mecarbilon the Phosphoate Dissociation and Motile Properties of the Recombinant Human beta-Cardiac Heavy-meromyosin. BIOPHYSICAL JOURNAL. 153A-153A.
2012

The Shaker-1 Mouse Myosin VIIa has a Drastically Compromised ATP Hydrolysis Mechanism. BIOPHYSICAL JOURNAL. 569A-570A.
2011

The Kinetic Mechanism of Mouse Myosin VIIA. JOURNAL OF BIOLOGICAL CHEMISTRY. 286:8819-8828.
Full Text via DOI: 10.1074/jbc.M110.163592 PMID: 21212272
2010

Influence of lever structure on myosin 5a walking. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107:2509-2514.
Full Text via DOI: 10.1073/pnas.0906907107 PMID: 20133809
2010

A Comparison of Mechanical Properties of Drosophila and Mouse Myosin 7a. BIOPHYSICAL JOURNAL. 725A-725A.
2010

Mechanical and Kinetic Properties of a Myosin 5-SAH Chimera. BIOPHYSICAL JOURNAL. 563A-564A.
2010

Mouse Myosinviia is a Monomeric, "slow" Motor with an Intermediate Duty Ratio. BIOPHYSICAL JOURNAL. 724A-725A.
2010

Myosin 5A Walking Mechanism: The Structural Basis of Slow ADP Dissociatin from the Lead Head. BIOPHYSICAL JOURNAL. 229A-229A.
2009

The SAH domain extends the functional length of the myosin lever. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106:22193-22198.
Full Text via DOI: 10.1073/pnas.0909851106 PMID: 20018767
2009

Switch 1 Mutation S217A Converts Myosin V into a Low Duty Ratio Motor. JOURNAL OF BIOLOGICAL CHEMISTRY. 284:2138-2149.
Full Text via DOI: 10.1074/jbc.M805530200 PMID: 19008235
2008

Direct observation of the mechanochemical coupling in myosin Va during processive movement. NATURE. 455:128-U99.
Full Text via DOI: 10.1038/nature07188 PMID: 18668042
2008

Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. JOURNAL OF BIOLOGICAL CHEMISTRY. 283:766-773.
Full Text via DOI: 10.1074/jbc.M704313200 PMID: 17965414
2007

Mutational analysis of the myosinV active site. BIOPHYSICAL JOURNAL. 493A-493A.
2007

The effect of IQ mutations upon the kinetics of ADP dissociation from ActomyosinV-HMM-ADP-Pi. BIOPHYSICAL JOURNAL. 637A-637A.
2006

Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. BIOCHEMISTRY. 45:13035-13045.
Full Text via DOI: 10.1021/bi060712n PMID: 17059220

full name

Eva Forgacs-Lonart

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