Kowalewska, Jolanta
- Associate Professor, Pathology and Anatomy
Overview
overview
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Dr. Jolanta Kowalewska MD, PhD is an associate professor of Pathology in the Department of Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA. She is board certified in anatomic and clinical pathology. She received her MD degree from Medical University in Warsaw, Poland, followed by clinical and anatomic pathology residency in Winthrop University Hospital, Mineola, NY (SUNY Stony Brook, NY). Subsequently, Dr Kowalewska pursued her subspecialty training in renal pathology at the University of Washington, Seattle, WA. Her PhD degree from University of Bialystok was awarded for her work in pathology of transplantation.
Dr Kowalewska held her faculty positions at the University of Washington, WA, University of Bialystok in Poland, and Cedars-Sinai Medical Center, Los Angeles, CA, and for the last 4 years at the EVMS. Her professional career has been focused on understanding mechanism of various renal diseases occurring in native and transplanted kidneys. Dr Kowalewska is actively involved in educational activities in EVMS including Medical School and the Pathologist's Assistant program. She serves and a faculty advisor for the Pathology Interest Group that promotes an interest on Pathology among the students from various programs.
She is also an active member in several national organizations, e.g. Unites States and Canadian Academy of Pathology, Renal Pathology Society, American Society of Nephrology, and the Association of Pathology Chairs.
Publications
selected publications
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2020Acute Transient Arteriopathy Mimicking Vascular Rejection in Allograft Kidneys. TRANSPLANTATION PROCEEDINGS.
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2020Educational Case: Proteinuria in elderly adult. ACADEMIC PATHOLOGY.
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2019Transplantation With APOL1 Risk Variant Kidney May Be Associated With Lifetime Risk for Recurrence of Focal Segmental Glomerulosclerosis: A Case Report and Review of Literature. TRANSPLANTATION PROCEEDINGS. 51:3077-3079.Full Text via DOI: 10.1016/j.transproceed.2019.04.056 PMID: 31324484
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2019
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2019Assessment of the Banff Working Group Classification of Definitive BK Polyomavirus Nephropathy. ASN meeting, Washington, DC.
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2018Diamond (TM) Mouse Model Displays Features of Diabetic Kidney Disease in Addition to Nash and NAC. HEPATOLOGY. 1016A-1016A.
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2018Acute Transient Arteriopathy Mimicking Vascular Rejection in Allograft Kidneys. ASN meeting, San Diego, CA.
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2018DIAMOND™ Mouse Model Displays Features of Diabetic Kidney Disease in Addition to NASH and NAC. The International Liver Conference, Paris, France.
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2018DIAMOND™ Mouse Model Displays Features of Diabetic Kidney Disease in Addition to NASH and NAC. American Association for the Study of Liver Diseases Annual Meeting, San Francisco, CA.
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2018MPGN And Sarcoidosis: A Rare Case Presentation. ASN meeting, San Diego, CA.
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2018ANCA-Associated Vasculitis Co-Occurrence With Systemic Sclerosis: A Case Report of a Rare Diagnostic Dilemma. JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS. 6:232470961878518.Full Text via DOI: 10.1177/2324709618785188
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2017Clinicopathologic correlations of renal pathology in adult population of Poland. NEPHROLOGY DIALYSIS TRANSPLANTATION. 32:209-218.Full Text via DOI: 10.1093/ndt/gfw365 PMID: 28339709
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2017Urinary System (Chapter 16). "Comparative Anatomy and Histology - A Mouse and Human Atlas",1st ed. Elsevier, Ltd.
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2017Urinary System (Chapter 16). "Comparative Anatomy and Histology - A Mouse and Human Atlas",1st ed. Elsevier, Ltd.
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2017Single center experience of subclinical rejections and BK nephropathies by kidney allografts' surveillance biopsies.. Advances in medical sciences. 62:110-115.Full Text via DOI: 10.1016/j.advms.2016.07.005 PMID: 28242482
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2016Kidney Biopsies May Help Predict Renal Function After Liver Transplantation. Transplantation. 100:2122-2128.Full Text via DOI: 10.1097/tp.0000000000001334
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2015
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2015Renal Biopsy Findings and PLA2R Status in Pregnancy-Associated Membranous Nephropathy. USCAP meeting, Boston, MA.
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2014Complement-mediated glomerular diseases. Dynamic Encyclopedia of Human Diseases. Elsevier, Ltd.
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2014Expression of IL-6 and its Receptor IL-6Rα is Increased in Kidney Allografts with Antibody Mediated Rejection. ASN meeting, Philadelphia, PA.
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2014Tocilizumab (Anti-IL6-Receptor) Therapy for Donor Specific Antibody (DSA+) Antibody Mediated Rejection (ABMR+) Resistant to IVIG + Rituximab Treatment. World Congress of Transplantation, San Francisco, CA.
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2013Pathology of recurrent diseases in kidney allografts: membranous nephropathy and focal segmental glomerulosclerosis. CURRENT OPINION IN ORGAN TRANSPLANTATION.
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2013Expression of macrophage markers in cryoglobulinemic glomerulonephritis - a possible role of CXCL9.. Advances in medical sciences. 58:394-400.Full Text via DOI: 10.2478/ams-2013-0030 PMID: 24084359
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2012Finding of Prostate Carcinoma at the Capsular End of a Prostate Needle Biopsy Does Not Predict Positive Capsular Margin on Radical Prostatectomy Specimen. USCAP meeting, Vancouver, BC, Canada.
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2012Frequency and associations of C4d deposits in explanted kidney allografts. ASN meeting, San Diego, CA.
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2012Expression of estrogen receptors α and β in paratesticular tissues in boys operated on for unilateral cryptorchidism between the 1st and 4th years of life.. Medical science monitor : international medical journal of experimental and clinical research. 18:CR630-4.Full Text via DOI: 10.12659/msm.883490 PMID: 23018357
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2011Bone as a source of whole organism vitality and regeneration. Folia Histochemica et Cytobiologica.
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2011Clinicopathological analysis of kidney diseases in adults: a report based on the databases from 7 nephropathological centers in Poland. European Congress of Pathology of the ESP, Helsinki, Finland.
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2011Cloudy peritoneal fluid at the time of dialysis initiation. Forum Nefrologiczne.
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2011Cryoglobulinemic glomerulonephritis - lessons from animal models. Folia Histochemica et Cytobiologica.
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2011Patterns of glomerular injury in kidneys infiltrated by lymphoplasmacytic neoplasms.. Human pathology. 42:896-903.Full Text via DOI: 10.1016/j.humpath.2010.09.009 PMID: 21288559
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2011Role of smooth muscle protein SM22α in glomerular epithelial cell injury.. American journal of physiology. Renal physiology. 300:F1026-42.Full Text via DOI: 10.1152/ajprenal.00187.2010 PMID: 21289056
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2011Temporal small-vessel inflammation in patients with giant cell arteritis: clinical course and preliminary immunohistopathologic characterization.. The Journal of rheumatology. 38:331-8.Full Text via DOI: 10.3899/jrheum.100455 PMID: 21123318
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2011The status of BK polyomavirus replication in adult renal transplant recipients in northeastern Poland.. TRANSPLANTATION PROCEEDINGS. 43:2976-84.Full Text via DOI: 10.1016/j.transproceed.2011.07.009 PMID: 21996205
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2010A new mouse model of progressive diabetic nephropathy. Journal of the American Society of Nephrology : JASN.
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2010Glomerulosclerosis Predicts Renal Function Following Liver Transplantation. ATC Congress, San Diego, CA.
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2010Loss of p16 protein and hypermethylation of p16 gene in bronchiolar columnar cell dysplasia. European Intercongress of Pathology of the ESP, Cracow, Poland.
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2009Acute transient arteriopathy in the early phase after the renal transplantation. USCAP meeting, Boston, MA.
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2009
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2009Inducible Rodent Models of Acquired Podocyte Diseases. American journal of physiology. Renal physiology.
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2009The Impact of Treatment on Late Renal Allograft Dysfunction in the Presence of C4d Staining. ATC Congress, San Diego, CA.
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2009The significance of C4d staining in renal allograft biopsies obtained 10 or more years post transplantation. Journal of the American Society of Nephrology : JASN.
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2009Deletion of activating Fcgamma receptors does not confer protection in murine cryoglobulinemia-associated membranoproliferative glomerulonephritis.. AMERICAN JOURNAL OF PATHOLOGY. 175:107-18.Full Text via DOI: 10.2353/ajpath.2009.081159 PMID: 19528347
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2009Imatinib suppresses cryoglobulinemia and secondary membranoproliferative glomerulonephritis.. Journal of the American Society of Nephrology : JASN. 20:68-77.Full Text via DOI: 10.1681/asn.2008010036 PMID: 19020005
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2008Association of C4d Staining in Late Renal Allografts with Donor Specific Antibodies and Graft Outcome. ASN Meeting, Philadelphia, PA.
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2008C4d staining in late renal allograft biopsies is strongly linked to allograft failure. ASN meeting, Philadelphia, PA.
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2008Fibrillary glomerulonephritis and immunotactoid glomerulopathy. Journal of the American Society of Nephrology : JASN.
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2008Reversal of Diabetic Nephropathy Is Accompanied by Podocyte Regeneration in BTBR ob/ob Mice. ASN meeting, Philadelphia, PA.
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2008
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2008Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients.. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 3:829-35.Full Text via DOI: 10.2215/cjn.03930907 PMID: 18372319
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2008Identification of platelet-derived growth factor D in human chronic allograft nephropathy.. Human pathology. 39:393-402.Full Text via DOI: 10.1016/j.humpath.2007.07.008 PMID: 18187181
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2008Protease nexin-1, tPA, and PAI-1 are upregulated in cryoglobulinemic membranoproliferative glomerulonephritis.. Journal of the American Society of Nephrology : JASN. 19:243-51.Full Text via DOI: 10.1681/asn.2007030367 PMID: 18199802
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2008Renin-angiotensin system blockade is renoprotective in immune complex-mediated glomerulonephritis.. Journal of the American Society of Nephrology : JASN. 19:1168-76.Full Text via DOI: 10.1681/asn.2007050607 PMID: 18337487
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2008VEGF inhibition and renal thrombotic microangiopathy.. NEW ENGLAND JOURNAL OF MEDICINE. 358:1129-36.Full Text via DOI: 10.1056/nejmoa0707330 PMID: 18337603
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2007Emerging paradigms in the renal pathology of viral diseases. Journal of the American Society of Nephrology : JASN.
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2007
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2007Leflunomide use in renal transplantation. Is it causing hemolytic syndrome. ATC, San Francisco, CA.
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2007Patterns of Glomerular Injury in Kidneys Infiltrated by Lymphoplasmacytic Neoplasms. USCAP meeting, San Diego, CA.
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2007Proteinuria and thrombotic microangiopathy secondary to anti-VEGF antibody (bevacizumab) therapy. ASN meeting, San Francisco, CA.
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2007Recent advances in glomerulonephritis. Current Diagnostic Pathology.
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2007Tubular Basement Membrane Immune Deposits in Polyoma Virus Nephropathy. ATC, San Francisco, CA.
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2007All-trans-retinoic acid aggravates cryoglobulin-associated membranoproliferative glomerulonephritis in mice.. NEPHROLOGY DIALYSIS TRANSPLANTATION. 22:3451-61.Full Text via DOI: 10.1093/ndt/gfm502 PMID: 17686814
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2007Localization of TGF-beta signaling intermediates Smad2, 3, 4, and 7 in developing and mature human and mouse kidney.. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 55:275-85.Full Text via DOI: 10.1369/jhc.6a7083.2006 PMID: 17142805
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2007Spectrum of renal pathology in hematopoietic cell transplantation: a series of 20 patients and review of the literature.. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2:1014-23.Full Text via DOI: 10.2215/cjn.01700407 PMID: 17702721
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2007Thymic stromal lymphopoietin transgenic mice develop cryoglobulinemia and hepatitis with similarities to human hepatitis C liver disease.. AMERICAN JOURNAL OF PATHOLOGY. 170:981-9.Full Text via DOI: 10.2353/ajpath.2007.060474 PMID: 17322382
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2007Tubular basement membrane immune deposits in association with BK polyomavirus nephropathy.. AMERICAN JOURNAL OF TRANSPLANTATION. 7:1552-60.Full Text via DOI: 10.1111/j.1600-6143.2007.01794.x PMID: 17425622
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2006A Clinicopathologic Study of Renal Manifestation after Bone Marrow Transplantation. USCAP meeting, San Antonio, TX.
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2006Characterization of a New Murine Model of Diabetic Nephropathy. ASN meeting, San Diego, CA.
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2006Clinical significance of Tubular Basement Membrane Immune Deposits in Polyoma Virus Nephropathy. ASN meeting, San Diego, CA.
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2006
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2006Imatinib attenuates cryoglobulin-associated membranoproliferative glomerulonephritis in mice. ASN meeting, San Diego, CA.
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2006Involvement of PN-1, tPA and PAI-1 in Murine Model of Cryoglobulin- Associated MPGN. ASN meeting, San Diego, CA.
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2006Retinoic Acid Aggravates Cryoglobulin-Associated Membranoproliferative Glomerulonephritis (MPGN) in Mice. ASN meeting, San Diego, CA.
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2006Tubular basement membrane deposits associated with polyoma virus nephropathy in renal allografts. USCAP meeting, Atlanta, GA.
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2006A clinicopathologic study of thrombotic microangiopathy in the setting of IgA nephropathy.. Clinical nephrology. 66:397-404.Full Text via DOI: 10.5414/cnp66397 PMID: 17176910
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2006Giant cell tubulitis with tubular basement membrane immune deposits: a report of two cases after cardiac valve replacement surgery.. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 1:920-4.Full Text via DOI: 10.2215/cjn.02201205 PMID: 17699308
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2006Membranous glomerulopathy with spherules: an uncommon variant with obscure pathogenesis.. AMERICAN JOURNAL OF KIDNEY DISEASES. 47:983-92.Full Text via DOI: 10.1053/j.ajkd.2006.03.004 PMID: 16731293
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2005A Clinicopathologic Study of Thrombotic Microangiopathy in the setting of IgA Nephropathy. USCAP meeting, San Antonio, TX.
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2005Expression of Genes of the Complement Activation Pathways in Murine Model of Membranoproliferative Glomerulonephritis (MPGN). ASN Meeting, Philadelphia, PA.
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2005Expression of Smad2, Smad3, Smad4 and Smad7 in Developing and Mature Murine and Human Kidneys. ASN meeting, Philadelphia, PA.
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2005Gene expression profile in murine model of membranoproliferative glomerulonephritis. National Kidney Foundation Clinical Meeting, Washington DC.
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2005Induction of Toll-Like Receptors in a Mouse Model of Membranoproliferative Glomerulonephritis. ASN meeting, Philadelphia, PA.
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2005
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2005IgA nephropathy with crescents in kidney transplant recipients.. AMERICAN JOURNAL OF KIDNEY DISEASES. 45:167-75.Full Text via DOI: 10.1053/j.ajkd.2004.09.030 PMID: 15696457
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2004Immunohistochemical assessment of MPO to quantify inflammatory activity in lupus nephritis. USCAP meeting, Vancouver, BC, Canada.
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2004Nephropathy in Macaques infected with Human, Simian and Simian-Human. ASN meeting, St Louis, MI.
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2004Potential role of protease nexin-1 and tissue plasminogen activator in murine model of MPGN. ASN meeting, St Louis, MI.
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2004Thymic stromal lymphopoietin (TSLP) transgenic mice develop mixed cryoglobulinemia and hepatitis mimicking human chronic hepatitis C disease. USCAP meeting, Vancouver, BC, Canada.
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2004Expression of nephrin in acquired forms of nephrotic syndrome in childhood.. PEDIATRIC NEPHROLOGY. 19:300-5.Full Text via DOI: 10.1007/s00467-003-1346-3 PMID: 14747939
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2003
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2003Crystals in podocytes: an unusual manifestation of systemic disease.. AMERICAN JOURNAL OF KIDNEY DISEASES. 42:605-11.Full Text via DOI: 10.1016/s0272-6386(03)00794-7 PMID: 12955694
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2003Safety and efficacy of intratracheal recombinant human Clara cell protein in a newborn piglet model of acute lung injury.. PEDIATRIC RESEARCH. 54:509-15.Full Text via DOI: 10.1203/01.pdr.0000081300.49749.87 PMID: 12815115
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2002Isolated Temporal Small Vessel Inflammation (TSVI): An Important Clue to the Diagnosis of Giant Cell Arteritis (GCA). 66th Annual meeting of the American College of Rheumatology, New Orleans, LA.
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2002Lymphocyte Repertoire of Temporal Small Vessel Inflammation (TSVI) Resembles Inflammatory Infiltrate in Giant Cell Arteritis. 2nd International Conference on Giant Cell Arteritis and Polymyalgia Rheumatica, Mayo Clinic, Rochester, MN.
Research
research overview
- Current research interests include BK polyomavirus nephropathy, glomerulonephritis and development of educational cases in pathology. Renal transplantation, Glomerulonephritis, Pathology, Urology, Gastroenterology and Hepatology
Contact
preferred title
- Associate Professor
full name
- Jolanta Kowalewska, MD, Ph.D.