Han, Joseph K.

Han, Joseph K.
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Positions

Chief of the Division of Rhinology & Endoscopic Sinus and Skull Base Surgery and the Division of Allergy, Otolaryngology-Head and Neck Surgery

Contact Info

hanjk@evms.edu

selected publications

2022

Long-term efficacy and safety of omalizumab for nasal polyposis in an open-label extension study. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 149:957-+.
Full Text via DOI: 10.1016/j.jaci.2021.07.045 PMID: 34530020
2020

Clinical Aspects of Sublingual Immunotherapy Tablets and Drops.. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
Full Text via DOI: 10.1016/j.anai.2019.12.025 PMID: 31923544
2019

Topical therapies for management of chronic rhinosinusitis: steroid implants. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. S22-S26.
Full Text via DOI: 10.1002/alr.22344 PMID: 31087636
2019

Bioabsorbable steroid-releasing implants in the frontal sinus ostia: a pooled analysis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 9:131-139.
Full Text via DOI: 10.1002/alr.22238 PMID: 30431709
2019

Efficacy and Safety of Dupilumab in Patients with Chronic Rhinosinusitis with Nasal Polyps: Results from the Randomized Phase 3 Sinus-24 Study. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. AB422-AB422.
2019

Analysis of Histopathological Endotyping for Chronic Rhinosinusitis Phenotypes Based on Comorbid Asthma and Allergic Rhinitis. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 33:507-512.
Full Text via DOI: 10.1177/1945892419846263 PMID: 31046407
2019

Answers to some common rhinologic questions. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 829-830.
Full Text via DOI: 10.1002/alr.22393 PMID: 31390490
2019

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. LANCET. 394:1638-1650.
Full Text via DOI: 10.1016/S0140-6736(19)31881-1 PMID: 31543428
2019

Establishing Urinary Leukotriene E-4 as a Diagnostic Biomarker for Chronic Rhinosinusitis with Comorbid Asthma and Atopy. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 161:764-769.
Full Text via DOI: 10.1177/0194599819871700 PMID: 31453737
2019

In-office Placement of Mometasone Furoate Sinus Implants for Recurrent Nasal Polyps: A Pooled Analysis. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 33:545-558.
Full Text via DOI: 10.1177/1945892419850924 PMID: 31117809
2019

NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 33:69-82.
Full Text via DOI: 10.1177/1945892418810281 PMID: 30477309
2018

Safety and Effectiveness of a Bioabsorbable Steroid-Releasing Implant for the Paranasal Sinus Ostia A Randomized Clinical Trial. JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY. 144:28-35.
Full Text via DOI: 10.1001/jamaoto.2017.1859 PMID: 29098299
2017

Ectopic Pituitary Adenomas Presenting as Sphenoid or Clival Lesions: Case Series and Management Recommendations. JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE. 78:120-124.
Full Text via DOI: 10.1055/s-0036-1592081 PMID: 28321374
2017

Time Course of Improvement in Individual Nasal Symptoms During a 2-Week Study of MP-AzeFlu in Patients with Seasonal Allergic Rhinitis (SAR). JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. AB253-AB253.
2017

EDITORIAL. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 219-220.
Full Text via DOI: 10.1002/alr.21930 PMID: 28297554
2016

Evaluation of the PROPEL (R) mini sinus implant for the treatment of frontal sinus disease. EXPERT OPINION ON DRUG DELIVERY. 13:1789-1793.
Full Text via DOI: 10.1080/17425247.2016.1250740 PMID: 27758142
2016

Randomized controlled trial of a bioabsorbable steroid-releasing implant in the frontal sinus opening. LARYNGOSCOPE. 126:2659-2664.
Full Text via DOI: 10.1002/lary.26140 PMID: 27363723
2016

Interleukin-9 and interleukin-17C in chronic rhinosinusitis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 6:841-847.
Full Text via DOI: 10.1002/alr.21745 PMID: 26989880
2016

RESOLVE: bioabsorbable steroid-eluting sinus implants for in-office treatment of recurrent sinonasal polyposis after sinus surgery: 6-month outcomes from a randomized, controlled, blinded study. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 6:573-581.
Full Text via DOI: 10.1002/alr.21741 PMID: 26992115
2016

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. S22-S209.
Full Text via DOI: 10.1002/alr.21695 PMID: 26889651
2016

Implantable Devices/Drugs in the Management of Nasal Polyps. RHINOSINUSITIS WITH NASAL POLYPOSIS. 79:131-137.
Full Text via DOI: 10.1159/000445179 PMID: 27466855
2015

Clinical Consensus Statement: Septoplasty with or without Inferior Turbinate Reduction. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 153:708-720.
Full Text via DOI: 10.1177/0194599815606435 PMID: 26527752
2015

Computed tomography imaging practice patterns in adult chronic rhinosinusitis: survey of the American Academy of Otolaryngology-Head and Neck Surgery and American Rhinologic Society membership. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 5:506-512.
Full Text via DOI: 10.1002/alr.21483 PMID: 25907412
2015

Clinical Practice Guideline: Allergic Rhinitis. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 152:S1-S43.
Full Text via DOI: 10.1177/0194599814561600 PMID: 25644617
2015

Clinical Practice Guideline: Allergic Rhinitis Executive Summary. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 152:197-206.
Full Text via DOI: 10.1177/0194599814562166 PMID: 25645524
2015

Untitled. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 771-772.
Full Text via DOI: 10.1002/alr.21643 PMID: 26334048
2014

RESOLVE: a randomized, controlled, blinded study of bioabsorbable steroid-eluting sinus implants for in-office treatment of recurrent sinonasal polyposis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 4:861-870.
Full Text via DOI: 10.1002/alr.21426 PMID: 25266981
2014

Endoscopic and Three-Dimensional Radiographic Imaging of the Pterygopalatine and Infratemporal Fossae: Improving Surgical Landmarks. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 123:111-116.
Full Text via DOI: 10.1177/0003489414523707 PMID: 24574466
2013

Sinus implants for chronic rhinosinusitis: technology evaluation. EXPERT OPINION ON DRUG DELIVERY. 10:1735-1748.
Full Text via DOI: 10.1517/17425247.2013.839654 PMID: 24088141
2013

Subclassification of chronic rhinosinusitis. LARYNGOSCOPE. 123:S15-S27.
Full Text via DOI: 10.1002/lary.23979 PMID: 23371324
2013

Bacterial pathogens in the nasopharynx, nasal cavity, and osteomeatal complex during wellness and viral infection. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 27:39-42.
Full Text via DOI: 10.2500/ajra.2013.27.3835 PMID: 23406599
2012

Clinical Consensus Statement: Appropriate Use of Computed Tomography for Paranasal Sinus Disease. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 147:808-816.
Full Text via DOI: 10.1177/0194599812463848 PMID: 23054429
2012

Effect of steroid-releasing sinus implants on postoperative medical and surgical interventions: an efficacy meta-analysis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 2:271-279.
Full Text via DOI: 10.1002/alr.21044 PMID: 22550039
2012

Advance II: A Prospective, Randomized Study Assessing Safety and Efficacy of Bioabsorbable Steroid-Releasing Sinus Implants. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 146:1004-1011.
Full Text via DOI: 10.1177/0194599811435968 PMID: 22301107
2012

Immunomodulatory treatments for aspirin exacerbated respiratory disease. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 26:134-140.
Full Text via DOI: 10.2500/ajra.2012.26.3748 PMID: 22487291
2011

Evidence for Distinct Histologic Profile of Nasal Polyps With and Without Eosinophilia. LARYNGOSCOPE. 121:2262-2267.
Full Text via DOI: 10.1002/lary.21969 PMID: 21898422
2011

Bacterial pathogens of acute sinusitis in the osteomeatal complex during common colds and wellness. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 1:356-360.
Full Text via DOI: 10.1002/alr.20080 PMID: 22287466
2011

Outcome results of endoscopic vs craniofacial resection of sinonasal malignancies: a systematic review and pooled-data analysis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 255-261.
Full Text via DOI: 10.1002/alr.20051 PMID: 22287429
2011

Microbiology of sinusitis: does allergy or endoscopic sinus surgery affect the microbiologic flora?. CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY. 19:199-203.
Full Text via DOI: 10.1097/MOO.0b013e328344f67a PMID: 21358332
2011

Nasal Polyps: Pathogenesis and Treatment Implications. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA. 44:685-+.
Full Text via DOI: 10.1016/j.otc.2011.03.005 PMID: 21621054
2011

Systematic Review of Topical Vasoconstrictors in Endoscopic Sinus Surgery. LARYNGOSCOPE. 422-432.
Full Text via DOI: 10.1002/lary.21286 PMID: 21271600
2010

Complications and Management of Septoplasty. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA. 43:897-+.
Full Text via DOI: 10.1016/j.otc.2010.04.013 PMID: 20599092
2010

Systemic Therapies in Managing Sinonasal Inflammation. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA. 43:551-+.
Full Text via DOI: 10.1016/j.otc.2010.02.013 PMID: 20525510
2010

Concentrated topical epinephrine is safe in endoscopic sinus surgery. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY. 24:140-142.
Full Text via DOI: 10.2500/ajra.2010.24.3454 PMID: 20338114
2010

Management of orbital complications in endoscopic sinus surgery. CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY. 18:32-36.
Full Text via DOI: 10.1097/MOO.0b013e328334a9f1 PMID: 19935067
2010

Subpopulation of Lymphocytes for Chronic Sinusitis. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. AB101-AB101.
2010

Level of Complete Dissection of the Ethmoid Sinuses With a Computed Tomographic Image Guidance System. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 119:17-21.
2010

Level of Complete Dissection of the Ethmoid Sinuses With a Computed Tomographic Image Guidance System. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 119:17-21.
Full Text via DOI: 10.1177/000348941011900103 PMID: 20128181
2010

Primary carcinoid tumor of the frontal sinus: A case report.
Full Text via DOI: 10.1177/014556131008901003 PMID: 20981647
2009

Pilot study of budesonide inhalant suspension irrigations for chronic eosinophilic sinusitis. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1352-1354.
Full Text via DOI: 10.1016/j.jaci.2009.09.018 PMID: 19910027
2009

Going to the next level: Health care's evolving expectations for evidence. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 551-554.
Full Text via DOI: 10.1016/j.otohns.2009.07.013 PMID: 19861188
2009

Various causes for frontal sinus obstruction. AMERICAN JOURNAL OF OTOLARYNGOLOGY. 30:80-82.
Full Text via DOI: 10.1016/j.amjoto.2008.02.009 PMID: 19239947
2008

Endoscopic Localization of the Anterior and Posterior Ethmoid Arteries. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 117:931-935.
2008

Analysis of transnasal endoscopic versus transseptal microscopic approach for excision of pituitary tumors. AMERICAN JOURNAL OF RHINOLOGY. 22:649-652.
Full Text via DOI: 10.2500/ajr.2008.22.3246 PMID: 19178807
2008

Microarray analysis of distinct gene transcription profiles in non-eosinophilic chronic sinusitis with nasal polyps. AMERICAN JOURNAL OF RHINOLOGY. 22:568-581.
Full Text via DOI: 10.2500/ajr.2008.22.3233 PMID: 19178793
2008

Management of retrobulbar hematoma. AMERICAN JOURNAL OF RHINOLOGY. 22:522-524.
Full Text via DOI: 10.2500/ajr.2008.22.3217 PMID: 18954513
2008

Introduction to pulmonary function. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA. 41:387-+.
Full Text via DOI: 10.1016/j.otc.2007.11.008 PMID: 18328376
2008

Distinct immune profiles of chronic inflammatory, eosinophilic, aspirin insensitive, and fungal sinusitis. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. S217-S217.
2008

Dual Action of TGF-beta 1 on Nasal-Polyp Derived Fibroblasts. LARYNGOSCOPE. 118:320-324.
Full Text via DOI: 10.1097/MLG.0b013e318159cc0b PMID: 18090870
2007

Asthma and the unified airway. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. S75-S106.
Full Text via DOI: 10.1016/j.otohns.2007.02.019 PMID: 17462497
2007

Executive summary: Asthma and the unified airway. OTOLARYNGOLOGY-HEAD AND NECK SURGERY. 136:699-706.
Full Text via DOI: 10.1016/j.otohns.2007.02.023 PMID: 17478201
2007

Initial surgical treatment for chronic frontal sinusitis: A pilot study. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 116:286-289.

principal investigator on

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)

full name

Joseph K. Han

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