Fore-Arcand, Lisa G.
- Professor / Education Specialist, Psychiatry and Behavioral Sciences
Contact Info
Publications
selected publications
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2020
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2019Human Beta-Cardiac Myosin Cardiomyopathy Mutations R712L and E497D Disrupt a Key Salt-Bridge in the Coupling Domain. BIOPHYSICAL JOURNAL. 264A-264A.
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2018N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. STRUCTURE. 26:1604-+.Full Text via DOI: 10.1016/j.str.2018.08.007 PMID: 30270174
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2018The shaker-1 mouse myosin VIIa deafness mutation results in a severely reduced rate of the ATP hydrolysis step. JOURNAL OF BIOLOGICAL CHEMISTRY. 293:819-829.Full Text via DOI: 10.1074/jbc.M117.810119 PMID: 29167268
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2017Biochemical and Mechanical Properties of the S532P and R712L Cardiomyopathy Myosin Mutants. BIOPHYSICAL JOURNAL. 556A-557A.
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2017Kinetic Characterization of the Mitochondrial Transporter Human Myosin XIX. BIOPHYSICAL JOURNAL. 264A-264A.
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2015Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity. JOURNAL OF MOLECULAR BIOLOGY. 427:3273-3284.Full Text via DOI: 10.1016/j.jmb.2015.07.026 PMID: 26297986
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2015Structural basis for drug-induced allosteric changes to human beta-cardiac myosin motor activity. NATURE COMMUNICATIONS. 6.Full Text via DOI: 10.1038/ncomms8974 PMID: 26246073
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2015Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine beta-Cardiac Myosin. BIOCHEMISTRY. 54:1963-1975.Full Text via DOI: 10.1021/bi5015166 PMID: 25680381
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2013Engineering of the Myosin Viia Nucleotide-Binding Pocket to Create Selective Sensitivity to N-6-Modified ADP Analogs. BIOPHYSICAL JOURNAL. 644A-644A.
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2013
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2012The Shaker-1 Mouse Myosin VIIa has a Drastically Compromised ATP Hydrolysis Mechanism. BIOPHYSICAL JOURNAL. 569A-570A.
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2012Use of Alcoholics Anonymous as Part of Medical School Education: Students’ and Educators’ Perspectives. SUBSTANCE ABUSE. 33:387-391.Full Text via DOI: 10.1080/08897077.2011.646110
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2011The Kinetic Mechanism of Mouse Myosin VIIA. JOURNAL OF BIOLOGICAL CHEMISTRY. 286:8819-8828.Full Text via DOI: 10.1074/jbc.M110.163592 PMID: 21212272
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2010Influence of lever structure on myosin 5a walking. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107:2509-2514.Full Text via DOI: 10.1073/pnas.0906907107 PMID: 20133809
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2010A Comparison of Mechanical Properties of Drosophila and Mouse Myosin 7a. BIOPHYSICAL JOURNAL. 725A-725A.
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2010Mechanical and Kinetic Properties of a Myosin 5-SAH Chimera. BIOPHYSICAL JOURNAL. 563A-564A.
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2010Mouse Myosinviia is a Monomeric, "slow" Motor with an Intermediate Duty Ratio. BIOPHYSICAL JOURNAL. 724A-725A.
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2010Myosin 5A Walking Mechanism: The Structural Basis of Slow ADP Dissociatin from the Lead Head. BIOPHYSICAL JOURNAL. 229A-229A.
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2009The SAH domain extends the functional length of the myosin lever. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106:22193-22198.Full Text via DOI: 10.1073/pnas.0909851106 PMID: 20018767
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2009Switch 1 Mutation S217A Converts Myosin V into a Low Duty Ratio Motor. JOURNAL OF BIOLOGICAL CHEMISTRY. 284:2138-2149.Full Text via DOI: 10.1074/jbc.M805530200 PMID: 19008235
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2009Psychiatry Clerkship Students' Preparation, Reflection, and Results on the NBME Psychiatry Subject Exam. ACADEMIC PSYCHIATRY. 33:120-124.Full Text via DOI: 10.1176/appi.ap.33.2.120
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2008Direct observation of the mechanochemical coupling in myosin Va during processive movement. NATURE. 455:128-U99.Full Text via DOI: 10.1038/nature07188 PMID: 18668042
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2008Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. JOURNAL OF BIOLOGICAL CHEMISTRY. 283:766-773.Full Text via DOI: 10.1074/jbc.M704313200 PMID: 17965414
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2008Proceedings of the 2007 Annual Meeting of the Association of Directors of Medical Student Education in Psychiatry (ADMSEP). TEACHING AND LEARNING IN MEDICINE. 20:197-200.Full Text via DOI: 10.1080/10401330801991949
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2007Mutational analysis of the myosinV active site. BIOPHYSICAL JOURNAL. 493A-493A.
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2007The effect of IQ mutations upon the kinetics of ADP dissociation from ActomyosinV-HMM-ADP-Pi. BIOPHYSICAL JOURNAL. 637A-637A.
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2007Abstracts from the Proceedings of the 2006 Annual Meeting of the Association of Directors of Medical Student Education in Psychiatry (ADMSEP). TEACHING AND LEARNING IN MEDICINE. 19:202-209.Full Text via DOI: 10.1080/10401330701334157
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2006Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. BIOCHEMISTRY. 45:13035-13045.Full Text via DOI: 10.1021/bi060712n PMID: 17059220
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2006Clinical Grading in Psychiatric Clerkships. ACADEMIC PSYCHIATRY. 30:104-109.Full Text via DOI: 10.1176/appi.ap.30.2.104
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2006Students' and Residents' Perceptions Regarding Technology in Medical Training. ACADEMIC PSYCHIATRY. 30:470-479.Full Text via DOI: 10.1176/appi.ap.30.6.470
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2004ALLIANCE FOR CLINICAL EDUCATION (ACE) PROCEEDINGS: Proceedings of the 2002 and 2003 Annual Meetings of the Association of Directors of Medical Student Education in Psychiatry (ADMSEP). TEACHING AND LEARNING IN MEDICINE. 16:388-396.Full Text via DOI: 10.1207/s15328015tlm1604_14
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2002Addiction professionals' attitudes regarding treatment of nicotine dependence.. The Jefferson Journal of Psychiatry. 17:46-52.
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2000Race, Age, and Back Pain as Factors in Completion of Residential Substance Abuse Treatment by Veterans. Psychiatric Services. 51:1157-1161.Full Text via DOI: 10.1176/appi.ps.51.9.1157
Contact
full name
- Lisa G. Fore-Arcand
