Krishna, Neel K.

Neel K. Krishna
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krishnnk@evms.edu

selected publications

2019

Peptide Inhibitor of Complement C1 (PIC1) Inhibits Growth of Pathogenic Bacteria. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 25:83-92.
Full Text via DOI: 10.1007/s10989-017-9651-z
2019

Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants.. PLOS ONE. 14.
Full Text via DOI: 10.1371/journal.pone.0226875 PMID: 31891617
2018

Peptide inhibitor of complement C1 modulates transfusion related acute lung injury in a novel rat model. MOLECULAR IMMUNOLOGY. 177-177.
Full Text via DOI: 10.1016/j.molimm.2018.06.129
2018

Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1. FRONTIERS IN IMMUNOLOGY. 9.
Full Text via DOI: 10.3389/fimmu.2018.00558 PMID: 29632531
2018

Peptide Inhibitor of Complement C1 (PIC1) demonstrates antioxidant activity via single electron transport (SET) and hydrogen atom transfer (HAT). PLOS ONE. 13.
Full Text via DOI: 10.1371/journal.pone.0193931 PMID: 29499069
2017

Therapeutic hypothermia modulates complement factor C3a and C5a levels in a rat model of hypoxic ischemic encephalopathy. PEDIATRIC RESEARCH. 81:654-662.
Full Text via DOI: 10.1038/pr.2016.271 PMID: 28002390
2017

Complement effectors, C5a and C3a, in cystic fibrosis lung fluid correlate with disease severity. PLOS ONE. 12.
Full Text via DOI: 10.1371/journal.pone.0173257 PMID: 28278205
2017

Discriminating the hemolytic risk of blood type A plasmas using the complement hemolysis using human erythrocytes (CHUHE) assay. TRANSFUSION. 57:517-524.
Full Text via DOI: 10.1111/trf.13948 PMID: 28000304
2017

Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1). PLOS ONE. 12.
Full Text via DOI: 10.1371/journal.pone.0170203 PMID: 28135312
2017

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds. PLOS ONE. 12.
Full Text via DOI: 10.1371/journal.pone.0170500 PMID: 28107529
2017

Peptide Inhibitor of Complement C1 Inhibits the Peroxidase Activity of Hemoglobin and Myoglobin.. International journal of peptides. 9454583.
Full Text via DOI: 10.1155/2017/9454583 PMID: 29081812
2016

Peptide inhibitor of complement C1 modulates acute intravascular hemolysis of mismatched red blood cells in rats. TRANSFUSION. 56:2133-2145.
Full Text via DOI: 10.1111/trf.13674 PMID: 27282513
2016

Discriminating complement-mediated acute transfusion reaction for type O plus red blood cells transfused into a B plus recipient with the complement hemolysis using human erythrocytes (CHUHE) assay. TRANSFUSION. 56:1845-1848.
Full Text via DOI: 10.1111/trf.13592 PMID: 26997226
2016

Eosinophil Quantitated Urine Kinetic A novel assay for assessment of eosinophilic esophagitis. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY. 116:435-439.
Full Text via DOI: 10.1016/j.anai.2016.02.011 PMID: 27017558
2015

Complement Effectors of Inflammation in Cystic Fibrosis Lung Fluid Correlate with Clinical Measures of Disease. PLOS ONE. 10.
Full Text via DOI: 10.1371/journal.pone.0144723 PMID: 26642048
2015

Discriminating Complement-Mediated Acute Transfusion Reaction (ATR) from Type O plus Erythrocytes Transfused into a B plus Recipient. TRANSFUSION. 130A-131A.
2015

Peptide Inhibitor of Complement C1 (PIC1) inhibits human red blood cell destruction in a rat model of acute intravascular hemolytic transfusion reaction (AIHTR). MOLECULAR IMMUNOLOGY. 154-154.
2015

Peptide Inhibitor of Complement significantly reduces brain injury in a rat model of neonatal hypoxic ischemic encephalopathy. MOLECULAR IMMUNOLOGY. 181-182.
2015

Therapeutic hypothermia modulates C3a and C5a levels in a rat model of neonatal hypoxic ischemic encephalopathy. MOLECULAR IMMUNOLOGY. 181-181.
2015

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats. PLOS ONE. 10.
Full Text via DOI: 10.1371/journal.pone.0132446 PMID: 26196285
2014

Complement inhibition significantly decreases red blood cell lysis in a rat model of acute intravascular hemolysis. TRANSFUSION. 54:2892-2900.
Full Text via DOI: 10.1111/trf.12695 PMID: 24806146
2014

Hyperglycemia inhibits complement-mediated immunological control of S. aureus in a rat model of peritonitis. MOLECULAR IMMUNOLOGY. 263-264.
2014

Development of a Novel Assay for Measuring Complement-induced Hemolysis. TRANSFUSION. 171A-171A.
2014

PeptiDe inhibitor of complement C1, a novel suppressor of classical pathway activation: mechanistic studies and clinical potential. FRONTIERS IN IMMUNOLOGY.
Full Text via DOI: 10.3389/fimmu.2014.00406 PMID: 25202312
2014

Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway. JOURNAL OF TRANSLATIONAL MEDICINE. 12.
Full Text via DOI: 10.1186/1479-5876-12-181 PMID: 24962100
2014

C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cells. VIRUS RESEARCH. 179:231-234.
Full Text via DOI: 10.1016/j.virusres.2013.11.007 PMID: 24246304
2014

Hyperglycemia Inhibits Complement-Mediated Immunological Control of S-aureus in a Rat Model of Peritonitis. JOURNAL OF DIABETES RESEARCH.
Full Text via DOI: 10.1155/2014/762051 PMID: 25610878
2013

Evolutionary dynamics of bovine coronaviruses: natural selection pattern of the spike gene implies adaptive evolution of the strains. JOURNAL OF GENERAL VIROLOGY. 94:2036-2049.
Full Text via DOI: 10.1099/vir.0.054940-0 PMID: 23804565
2013

A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility. MOLECULAR IMMUNOLOGY. 53:132-139.
Full Text via DOI: 10.1016/j.molimm.2012.07.012 PMID: 22906481
2013

Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing.. Results in immunology. 114-21.
Full Text via DOI: 10.1016/j.rinim.2013.10.004 PMID: 24600566
2012

Inhibition of ABO incompatibility using a novel small peptide. IMMUNOBIOLOGY. 1178-1179.
Full Text via DOI: 10.1016/j.imbio.2012.08.143
2012

Role of Molecular Diagnostics in the Management of Infectious Disease Emergencies. MEDICAL CLINICS OF NORTH AMERICA. 96:1067-+.
Full Text via DOI: 10.1016/j.mcna.2012.08.005 PMID: 23102477
2012

Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus. JOURNAL OF TRANSLATIONAL MEDICINE. 10.
Full Text via DOI: 10.1186/1479-5876-10-35 PMID: 22390383
2010

Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat protein. MOLECULAR IMMUNOLOGY. 48:305-313.
2010

Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat protein. MOLECULAR IMMUNOLOGY. 2259-2259.
Full Text via DOI: 10.1016/j.molimm.2010.05.185
2010

Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation. MOLECULAR IMMUNOLOGY. 47:792-798.
Full Text via DOI: 10.1016/j.molimm.2009.10.006 PMID: 19896716
2010

Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat protein. MOLECULAR IMMUNOLOGY. 48:305-313.
Full Text via DOI: 10.1016/j.molimm.2010.07.012 PMID: 20728940
2009

Human astrovirus coat protein binds C1q and MBL inhibiting the classical and the lectin pathways of complement activation. MOLECULAR IMMUNOLOGY. 2824-2824.
Full Text via DOI: 10.1016/j.molimm.2009.05.203
2008

Human Astrovirus Coat Protein: A Novel C1 Inhibitor. CURRENT TOPICS IN COMPLEMENT II. 632:237-251.
Full Text via DOI: 10.1007/978-0-387-78952-1_17 PMID: 19025126
2008

Human astrovirus coat protein inhibits serum complement activation via C1, the first component of the classical pathway. JOURNAL OF VIROLOGY. 82:817-827.
Full Text via DOI: 10.1128/JVI.01847-07 PMID: 17959658
2005

Complex formation among murine cytomegalovirus US22 proteins encoded by genes M139, M140, and M141. JOURNAL OF VIROLOGY. 79:3525-3535.
Full Text via DOI: 10.1128/JVI.79.6.3525-3535.2005 PMID: 15731247
2005

Identification of structural domains involved in astrovirus capsid biology. VIRAL IMMUNOLOGY. 17-26.

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Neel K. Krishna

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