Deutsch, Stephen I.

Deutsch, Stephen I.
Close

Contact Info

deutscsi@evms.edu

EVMS Directory Profile

selected publications

2020

Glycine transporter type 1 (GlyT1) inhibition improves conspecific-provoked immobility in BALB/c mice: Analysis of corticosterone response and glucocorticoid gene expression in cortex and hippocampus.. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 99.
Full Text via DOI: 10.1016/j.pnpbp.2020.109869 PMID: 31962186
2019

Collaborative interdisciplinary approaches for a heterogeneous group of neurodevelopmental disorders; A "Way" forward!. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 122-123.
Full Text via DOI: 10.1016/j.pnpbp.2019.03.011 PMID: 30930137
2019

Metabotropic functions of the NMDA receptor and an evolving rationale for exploring NR2A-selective positive allosteric modulators for the treatment of autism spectrum disorder. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 142-160.
Full Text via DOI: 10.1016/j.pnpbp.2018.11.017 PMID: 30481555
2019

Understanding facial expressivity in autism spectrum disorder: An inside out review of the biological basis and clinical implications. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 401-417.
Full Text via DOI: 10.1016/j.pnpbp.2018.05.009 PMID: 29777730
2019

Sexuality in the Autism Spectrum Study (SASS): Reports from Young Adults and Parents. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS. 49:3638-3655.
Full Text via DOI: 10.1007/s10803-019-04077-y PMID: 31127485
2018

Neuromotor and cognitive responses of adults with autism spectrum disorder compared to neurotypical adults. EXPERIMENTAL BRAIN RESEARCH. 236:2321-2332.
Full Text via DOI: 10.1007/s00221-018-5300-9 PMID: 29876630
2017

Immobility in the Presence of a Social Stressor is Unrelated to Corticosterone Response and General Locomotor Activity in the Balb/c Mouse. NEUROPSYCHOPHARMACOLOGY. S566-S567.
2017

Sugarcoated Perineuronal Nets Regulate "GABAergic" Transmission: Bittersweet Hypothesis in Autism Spectrum Disorder. CLINICAL NEUROPHARMACOLOGY. 120-130.
Full Text via DOI: 10.1097/WNF.0000000000000209 PMID: 28277443
2016

Age-Dependent Effects on Social Interaction of Nmda GluN2A Receptor Subtype-Selective Antagonism. NEUROPSYCHOPHARMACOLOGY. S343-S344.
2016

Age-dependent effects on social interaction of NMDA GluN2A receptor subtype-selective antagonism. BRAIN RESEARCH BULLETIN. 125:159-167.
Full Text via DOI: 10.1016/j.brainresbull.2016.06.017 PMID: 27378651
2016

Experimental Assessment of Mouse Sociability Using an Automated Image Processing Approach. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS.
Full Text via DOI: 10.3791/52508 PMID: 27213937
2016

Characterization of gait and olfactory behaviors in the Balb/c mouse model of autism spectrum disorders. BRAIN RESEARCH BULLETIN. 122:29-34.
Full Text via DOI: 10.1016/j.brainresbull.2016.02.017 PMID: 26917431
2016

The 15q13.3 deletion syndrome: Deficient alpha(7)-containing nicotinic acetylcholine receptor-mediated neurotransmission in the pathogenesis of neurodevelopmental disorders. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 64:109-117.
Full Text via DOI: 10.1016/j.pnpbp.2015.08.001 PMID: 26257138
2015

Characterization of Olfactory and Gait Behaviors in the Balb/c Mouse Model of Autism Spectrum Disorders. NEUROPSYCHOPHARMACOLOGY. S128-S129.
2015

The alpha(7) nicotinic acetylcholine receptor: A mediator of pathogenesis and therapeutic target in autism spectrum disorders and Down syndrome. BIOCHEMICAL PHARMACOLOGY. 363-377.
Full Text via DOI: 10.1016/j.bcp.2015.06.005 PMID: 26074265
2015

Effects of VU0410120, a novel GlyT1 inhibitor, on measures of sociability, cognition and stereotypic behaviors in a mouse model of autism. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 61:10-17.
Full Text via DOI: 10.1016/j.pnpbp.2015.03.003 PMID: 25784602
2015

NMDA receptor activation regulates sociability by its effect on mTOR signaling activity. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 60:60-65.
Full Text via DOI: 10.1016/j.pnpbp.2015.02.009 PMID: 25703582
2015

A Trial of D-Cycloserine to Treat the Social Deficit in Older Adolescents and Young Adults With Autism Spectrum Disorders. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES. 27:133-138.
Full Text via DOI: 10.1176/appi.neuropsych.13070155 PMID: 25923852
2014

VU0410120, an Inhibitor of the Glycine Transporter 1 (GlyT1), Improves Sociability and Cognition in the BALB/c Mouse Model of ASD, while Eliciting Stereotypic Behaviors in the Swiss Webster Strain. NEUROPSYCHOPHARMACOLOGY. S136-S137.
2014

Targeting the alpha(7) nicotinic acetylcholine receptor to prevent progressive dementia and improve cognition in adults with Down's syndrome. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 131-139.
Full Text via DOI: 10.1016/j.pnpbp.2014.05.011 PMID: 24865150
2014

A Trial of D-Cycloserine to Treat Stereotypies in Older Adolescents and Young Adults With Autism Spectrum Disorder. CLINICAL NEUROPHARMACOLOGY. 69-72.
Full Text via DOI: 10.1097/WNF.0000000000000033 PMID: 24824660
2014

NMDA receptors on the surface of cancer cells: Target for chemotherapy?. BIOMEDICINE & PHARMACOTHERAPY. 493-496.
Full Text via DOI: 10.1016/j.biopha.2014.03.012 PMID: 24751001
2014

Rapamycin improves sociability in the BTBR T(+)Itpr3(tf)/J mouse model of autism spectrum disorders. BRAIN RESEARCH BULLETIN. 100:70-75.
Full Text via DOI: 10.1016/j.brainresbull.2013.11.005 PMID: 24295733
2014

Safety of paliperidone extended-release in patients with schizophrenia or schizoaffective disorder and hepatic disease.. Clinical schizophrenia & related psychoses. 8-20.
Full Text via DOI: 10.3371/CSRP.AMCA.021513 PMID: 23428785
2013

A Trial of D-Cycloserine to Treat the Social Deficit in Older Adolescents and Young Adults with Autism Spectrum Disorders. NEUROPSYCHOPHARMACOLOGY. S505-S506.
2013

Rapamycin, an Inhibitor of mTORC1 Signaling Activity, Improved Measures of Sociability in the BTBR T+Itpr3tf/J Mouse Model of Autism Spectrum Disorder. NEUROPSYCHOPHARMACOLOGY. S567-S568.
2013

Clinical Outcomes of Mild Isolated Cerebral Ventriculomegaly in the Presence of Other Neurodevelopmental Risk Factors. JOURNAL OF ULTRASOUND IN MEDICINE. 32:1933-1938.
Full Text via DOI: 10.7863/ultra.32.11.1933 PMID: 24154896
2013

Balb/c mice treated with D-cycloserine arouse increased social interest in conspecifics. BRAIN RESEARCH BULLETIN. 99:95-99.
Full Text via DOI: 10.1016/j.brainresbull.2013.10.006 PMID: 24157954
2013

Targeting alpha-7 nicotinic neurotransmission in schizophrenia: A novel agonist strategy. SCHIZOPHRENIA RESEARCH. 148:138-144.
Full Text via DOI: 10.1016/j.schres.2013.05.023 PMID: 23768813
2013

D-Cycloserine improves sociability in the BTBR T+Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling. BRAIN RESEARCH BULLETIN. 96:62-70.
Full Text via DOI: 10.1016/j.brainresbull.2013.05.003 PMID: 23685206
2013

Neural basis of implicit memory for socio-emotional information in schizophrenia. PSYCHIATRY RESEARCH. 206:173-180.
Full Text via DOI: 10.1016/j.psychres.2012.10.005 PMID: 23123045
2013

PATHOPHYSIOLOGICAL MECHANISMS OF POST PARTUM DEPRESSION. ANNALS OF BEHAVIORAL MEDICINE. S300-S300.
2012

D-Cycloserine Improves Sociability and Spontaneous Stereotypic Behaviors in 4-Week Old Mice. BIOLOGICAL PSYCHIATRY. 299S-299S.
2012

D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice. BRAIN RESEARCH. 1439:96-107.
Full Text via DOI: 10.1016/j.brainres.2011.12.040 PMID: 22261249
2011

Genetically inbred Balb/c mice differ from outbred Swiss Webster mice on discrete measures of sociability: relevance to a genetic mouse model of autism spectrum disorders. AUTISM RESEARCH. 4:393-400.
Full Text via DOI: 10.1002/aur.218 PMID: 21882363
2011

Pharmacotherapeutic Implications of the Association Between Genomic Instability at Chromosome 15q13.3 and Autism Spectrum Disorders. CLINICAL NEUROPHARMACOLOGY. 203-205.
Full Text via DOI: 10.1097/WNF.0b013e31823a1247 PMID: 22094647
2011

Complex effects of mGluR5 antagonism on sociability and stereotypic behaviors in mice: Possible implications for the pharmacotherapy of autism spectrum disorders. BRAIN RESEARCH BULLETIN. 86:152-158.
Full Text via DOI: 10.1016/j.brainresbull.2011.08.001 PMID: 21840381
2011

Selective mGluR5 antagonism attenuates the stress-induced reduction of MK-801's antiseizure potency in the genetically inbred Balb/c mouse. EPILEPSY & BEHAVIOR. 21:352-355.
Full Text via DOI: 10.1016/j.yebeh.2011.03.026 PMID: 21683659
2011

D-Cycloserine enhances social exploration in the Balb/c mouse. BRAIN RESEARCH BULLETIN. 85:141-144.
Full Text via DOI: 10.1016/j.brainresbull.2011.03.004 PMID: 21396991
2011

D-Cycloserine improves the impaired sociability of the Balb/c mouse. BRAIN RESEARCH BULLETIN. 84:8-11.
Full Text via DOI: 10.1016/j.brainresbull.2010.10.006 PMID: 20970484
2011

D-serine improves dimensions of the sociability deficit of the genetically-inbred Balb/c mouse strain. BRAIN RESEARCH BULLETIN. 84:12-16.
Full Text via DOI: 10.1016/j.brainresbull.2010.10.010 PMID: 21056638
2011

The Mental Status Exam in Talmudic Medicine. CNS SPECTRUMS. 21-22.
Full Text via DOI: 10.1017/S1092852912000120 PMID: 24725298
2010

MK-801, a noncompetitive NMDA receptor antagonist, elicits circling behavior in the genetically inbred Balb/c mouse strain. BRAIN RESEARCH BULLETIN. 83:337-339.
Full Text via DOI: 10.1016/j.brainresbull.2010.08.014 PMID: 20813169
2010

Attention to Gaze and Emotion in Schizophrenia. NEUROPSYCHOLOGY. 24:711-720.
Full Text via DOI: 10.1037/a0019562 PMID: 20873932
2010

Locomotor activity of the genetically inbred Balb/c mouse strain is suppressed by a socially salient stimulus. BRAIN RESEARCH BULLETIN. 83:255-256.
Full Text via DOI: 10.1016/j.brainresbull.2010.07.006 PMID: 20637841
2010

Cerebral Ventricular Asymmetry and Ventriculomegaly Interact to Increase Risk for Schizophrenia: A Case Report and Recommendation for Routine Fetal Sonography. CNS SPECTRUMS. 574-578.
Full Text via DOI: 10.1017/S1092852900000547
2010

Cholinergic Abnormalities in Autism: Is There a Rationale for Selective Nicotinic Agonist Interventions?. CLINICAL NEUROPHARMACOLOGY. 114-120.
Full Text via DOI: 10.1097/WNF.0b013e3181d6f7ad PMID: 20190638
2010

Does subtle disturbance of neuronal migration contribute to schizophrenia and other neurodevelopmental disorders? Potential genetic mechanisms with possible treatment implications. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 281-287.
Full Text via DOI: 10.1016/j.euroneuro.2010.02.005 PMID: 20207112
2010

NMDA NR2B subtype-selective receptor antagonists fail to antagonize electrically-precipitated seizures and elicit popping in mice. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 20:207-210.
Full Text via DOI: 10.1016/j.euroneuro.2009.11.008 PMID: 20022475
2010

Regulation of Intermittent Oscillatory Activity of Pyramidal Cell Neurons by GABA Inhibitory Interneurons is Impaired in Schizophrenia: Rationale for Pharmacotherapeutic GABAergic Interventions. ISRAEL JOURNAL OF PSYCHIATRY AND RELATED SCIENCES. 47:17-+.
PMID: 20686196
2010

Regulation of Intermittent Oscillatory Activity of Pyramidal Cell Neurons by GABA Inhibitory Interneurons is Impaired in Schizophrenia: Rationale for Pharmacotherapeutic GABAergic Interventions. ISRAEL JOURNAL OF PSYCHIATRY AND RELATED SCIENCES. 47:17-+.
2009

Genetically inbred Balb/C mice are more sensitive to an effect of flurazepam and more resistant to an effect of stress than a genetically outbred mouse strain. EPILEPSY & BEHAVIOR. 16:415-417.
Full Text via DOI: 10.1016/j.yebeh.2009.08.013 PMID: 19762285

full name

Stephen I. Deutsch

visualizations

Recent publications and grants in Researchers@EVMS

Co-author Network

research areas