Pepe, Gerald J.

Pepe, Gerald J.
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Positions

Professor and Chair, Physiological Sciences

Contact Info

pepegj@evms.edu

selected publications

2022

Placental sFlt-1 Gene Delivery in Early Primate Pregnancy Suppresses Uterine Spiral Artery Remodeling. ENDOCRINOLOGY. 163.
Full Text via DOI: 10.1210/endocr/bqac012 PMID: 35134145
2022

B-flow/spatiotemporal image correlation M-mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling. ULTRASOUND IN OBSTETRICS & GYNECOLOGY. 59:358-364.
Full Text via DOI: 10.1002/uog.23753 PMID: 34358371
2019

Vascular Endothelial Growth Factor Delivery to Placental Basal Plate Promotes Uterine Artery Remodeling in the Primate. ENDOCRINOLOGY. 160:1492-1505.
Full Text via DOI: 10.1210/en.2019-00059 PMID: 31002314
2018

A Non-Human Primate Model of Defective Uterine Spiral Artery Remodeling That Replicates Symptoms of Preeclampsia (PE) and Fetal Growth Restriction (FGR).. REPRODUCTIVE SCIENCES. 237A-237A.
2017

Adipose and Liver Function in Primate Offspring with Insulin Resistance Induced by Estrogen Deprivation in Utero.. Endocrinology, diabetes and metabolism journal.
PMID: 29983904
2016

Estrogen Suppresses Interaction of Melanocortin 2 Receptor and Its Accessory Protein in the Primate Fetal Adrenal Cortex. ENDOCRINOLOGY. 157:4588-4601.
Full Text via DOI: 10.1210/en.2016-1562 PMID: 27779913
2016

Insulin resistance elicited in postpubertal primate offspring deprived of estrogen in utero. ENDOCRINE. 54:788-797.
Full Text via DOI: 10.1007/s12020-016-1145-9 PMID: 27770396
2016

Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring. JOURNAL OF ENDOCRINOLOGY. 230:171-183.
Full Text via DOI: 10.1530/JOE-15-0530 PMID: 27207093
2016

Estrogen Regulation of Fetal Adrenal Cortical Zone-Specific Development in the Nonhuman Primate Impacts Adrenal Production of Androgen and Cortisol and Response to ACTH in Females in Adulthood. ENDOCRINOLOGY. 157:1905-1913.
Full Text via DOI: 10.1210/en.2015-2087 PMID: 26990066
2016

Estrogen Regulation of Fetal Adrenal Cortical-Zone Specific Development in the Nonhuman Primate Impacts Adrenal Production of Androgen and Cortisol and Response to ACTH in Adulthood.. REPRODUCTIVE SCIENCES. 70A-70A.
2016

Suppression of Melanocortin 2 Receptor and Melanocortin 2 Receptor Accessory Protein Interaction by Estrogen in the Nonhuman Primate Fetal Adrenal Cortex.. REPRODUCTIVE SCIENCES. 92A-92A.
2016

Assessment of Protein Expression by Proximity Ligation Assay in the Nonhuman Primate Endometrium, Placenta, and Fetal Adrenal in Response to Estrogen. ESTROGEN RECEPTORS: METHODS AND PROTOCOLS. 1366:149-161.
Full Text via DOI: 10.1007/978-1-4939-3127-9_12 PMID: 26585133
2016

Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring. JOURNAL OF ENDOCRINOLOGY. 230:171-183.
Full Text via DOI: 10.1530/joe-15-0530 PMID: 27207093
2015

Estrogen promotes luteolysis by redistributing prostaglandin F2 alpha receptors within primate luteal cells. REPRODUCTION. 149:453-464.
Full Text via DOI: 10.1530/REP-14-0412 PMID: 25687410
2015

Fetal Programming in the Nonhuman Primate: Impact of Estrogen Deprivation In Utero on Insulin Sensitivity in Offspring After Birth. REPRODUCTIVE SCIENCES. 168A-168A.
2015

Placental Estrogen Suppresses Cyclin D1 Expression in the Nonhuman Primate Fetal Adrenal Cortex. REPRODUCTIVE SCIENCES. 101A-101A.
2015

Estrogen promotes luteolysis by redistributing prostaglandin F2α receptors within primate luteal cells. REPRODUCTION. 149:453-464.
Full Text via DOI: 10.1530/rep-14-0412 PMID: 25687410
2014

Placental Estrogen Suppresses Cyclin D1 Expression in the Nonhuman Primate Fetal Adrenal Cortex. ENDOCRINOLOGY. 155:4774-4784.
Full Text via DOI: 10.1210/en.2014-1221 PMID: 25247468
2013

Regulation of Baboon Fetal Ovarian Development by Placental Estrogen: Onset of Puberty Is Delayed in Offspring Deprived of Estrogen In Utero. BIOLOGY OF REPRODUCTION. 89.
Full Text via DOI: 10.1095/biolreprod.112.107318 PMID: 24132960
2013

PATHOPHYSIOLOGICAL MECHANISMS OF POST PARTUM DEPRESSION. ANNALS OF BEHAVIORAL MEDICINE. S300-S300.
2012

Prematurely Elevating Estradiol in Early Baboon Pregnancy Suppresses Uterine Artery Remodeling and Expression of Extravillous Placental Vascular Endothelial Growth Factor and alpha 1 beta 1 and alpha 5 beta 1 Integrins. ENDOCRINOLOGY. 153:2897-2906.
Full Text via DOI: 10.1210/en.2012-1141 PMID: 22495671
2012

Suppression of trophoblast uterine spiral artery remodeling by estrogen during baboon pregnancy: impact on uterine and fetal blood flow dynamics. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 302:H1936-H1944.
Full Text via DOI: 10.1152/ajpheart.00590.2011 PMID: 22427518
2012

D-Cycloserine Improves Sociability and Spontaneous Stereotypic Behaviors in 4-Week Old Mice. BIOLOGICAL PSYCHIATRY. 299S-299S.
2012

Developmental Expression of Cell Cycle Regulators in the Primate Fetal Adrenal Cortex.. REPRODUCTIVE SCIENCES. 347A-347A.
2012

Suppression of Trophoblast Uterine Spiral Artery Remodeling by Estrogen during Baboon Pregnancy: Impact on Uterine and Fetal Blood Flow Dynamics.. REPRODUCTIVE SCIENCES. 85A-85A.
2012

D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice. BRAIN RESEARCH. 1439:96-107.
Full Text via DOI: 10.1016/j.brainres.2011.12.040 PMID: 22261249
2011

Development of the Baboon Fetal Epididymis after Estrogen Suppression In Utero during the Second Half of Gestation. REPRODUCTIVE SCIENCES. 370A-370A.
2011

Expression of P-450 Aromatase, Estrogen Receptor alpha and beta and alpha-Inhibin in the Fetal Baboon Testis after Estrogen Suppression during the Second Half of Gestation. REPRODUCTIVE SCIENCES. 174A-174A.
2011

Fetal Programming in the Baboon: Impact of Estrogen Deprivation In Utero on Insulin Signaling and Reproductive Development after Birth. REPRODUCTIVE SCIENCES. 204A-204A.
2011

Expression of P-450 aromatase, estrogen receptor alpha and beta, and alpha-inhibin in the fetal baboon testis after estrogen suppression during the second half of gestation. ENDOCRINE. 39:75-82.
Full Text via DOI: 10.1007/s12020-010-9414-5 PMID: 21061091
2010

Divergent Regulation of Angiopoietin-1 and-2, Tie-2, and Thrombospondin-1 Expression by Estrogen in the Baboon Endometrium. MOLECULAR REPRODUCTION AND DEVELOPMENT. 77:430-438.
Full Text via DOI: 10.1002/mrd.21163 PMID: 20140967
2010

Divergent Regulation of Angiopoietin-1 and-2,Tie-2, and Thrombospondin-1 Expression by Estrogen in the Baboon Endometrium.. REPRODUCTIVE SCIENCES. 138A-138A.
2010

Estrogen Regulates Expression of Cell Cycle Regulators in the Primate Fetal Adrenal Gland.. REPRODUCTIVE SCIENCES. 354A-355A.
2010

Uterine and Fetal Blood Flow Indices and Fetal Growth Assessment after Chronic Estrogen Suppression in the Second Half of Baboon Pregnancy.. REPRODUCTIVE SCIENCES. 357A-357A.
2010

Uterine and fetal blood flow indexes and fetal growth assessment after chronic estrogen suppression in the second half of baboon pregnancy. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 298:H881-H889.
Full Text via DOI: 10.1152/ajpheart.00611.2009 PMID: 20023123
2010

Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 54:397-407.
Full Text via DOI: 10.1387/ijdb.082758ea PMID: 19876841
2009

Estrogen Promotes Germ Cell and Seminiferous Tubule Development in the Baboon Fetal Testis. BIOLOGY OF REPRODUCTION. 81:406-414.
Full Text via DOI: 10.1095/biolreprod.108.073494 PMID: 19403930
2009

Regulation of Baboon Fetal Pituitary Prolactin Expression by Estrogen. BIOLOGY OF REPRODUCTION. 80:1189-1195.
Full Text via DOI: 10.1095/biolreprod.108.072785 PMID: 19176882
2009

Developmental regulation of the expression of the transferrin receptor and Ki67 in oocytes of the baboon fetal ovary by estrogen. ENDOCRINE. 35:177-183.
Full Text via DOI: 10.1007/s12020-008-9133-3 PMID: 19156547
2009

Divergent Regulation of Vascular Endothelial Growth Factor, Angiopoictin-1 and-2 and Thrombospondin-1 Expression by Estrogen in the Baboon Endometrium. REPRODUCTIVE SCIENCES. 185A-185A.
2009

Regulation of Baboon Fetal Pituitary Prolactin Expression by Estrogen. REPRODUCTIVE SCIENCES. 193A-193A.
2009

Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. ENDOCRINE. 35:81-88.
Full Text via DOI: 10.1007/s12020-008-9128-0 PMID: 19016353
2009

Divergent Regulation of Vascular Endothelial Growth Factor, Angiopoietin-1 and-2, and Thrombospondin-1 Expression by Estrogen in the Baboon Endometrium.. BIOLOGY OF REPRODUCTION. 55-55.
2009

Estrogen Promotes Germ Cell and Seminiferous Tubule Development in the Baboon Fetal Testis. BIOLOGY OF REPRODUCTION. 202-202.
2008

Regulation of Expression of Microvillus Membrane Proteins by Estrogen in Baboon Fetal Ovarian Oocytes. BIOLOGY OF REPRODUCTION. 79:1160-1168.
Full Text via DOI: 10.1095/biolreprod.108.067900 PMID: 18716290
2008

Vascular Endothelial Growth Factor Mediates the Estrogen-Induced Breakdown of Tight Junctions between and Increase in Proliferation of Microvessel Endothelial Cells in the Baboon Endometrium. ENDOCRINOLOGY. 149:6076-6083.
Full Text via DOI: 10.1210/en.2008-0521 PMID: 18687775
2008

Suppression of extravillous trophoblast vascular endothelial growth factor expression and uterine spiral artery invasion by estrogen during early baboon pregnancy. ENDOCRINOLOGY. 149:5078-5087.
Full Text via DOI: 10.1210/en.2008-0116 PMID: 18566115
2008

Oocytes of baboon fetal primordial ovarian follicles express estrogen receptor beta mRNA. ENDOCRINE. 33:254-260.
Full Text via DOI: 10.1007/s12020-008-9081-y PMID: 18484193
2008

Regulation of placental villous angiopoietin-1 and-2 expression by estrogen during baboon pregnancy. MOLECULAR REPRODUCTION AND DEVELOPMENT. 75:504-511.
Full Text via DOI: 10.1002/mrd.20721 PMID: 18022824
2008

Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle (VSMC) migration as an early step in microvessel remodeling. REPRODUCTIVE SCIENCES. 84A-84A.
2007

Regulation of expression and localisation of the Na+/H+ exchanger (NHE) 3 and the NHE regulatory factor 2 in baboon placental syncytiotrophoblast by oestrogen. PLACENTA. 28:878-888.
Full Text via DOI: 10.1016/j.placenta.2007.01.003 PMID: 17336377
2007

Placental villous vascular endothelial growth factor expression and vascularization after estrogen suppression during the last two-thirds of baboon pregnancy. ENDOCRINE. 31:260-267.
Full Text via DOI: 10.1007/s12020-007-0036-5 PMID: 17906373
2007

Differential expression of placental villous angiopoietin-1 and-2 during early, mid and late baboon pregnancy. PLACENTA. 28:212-218.
Full Text via DOI: 10.1016/j.placenta.2006.02.003 PMID: 16630655
2007

Developmental expression of cell cycle regulators in the baboon fetal adrenal gland. JOURNAL OF ENDOCRINOLOGY. 192:237-247.
Full Text via DOI: 10.1677/joe.1.06769 PMID: 17210761
2006

Developmental regulation of the sodium/hydrogen ion exchangers and their regulatory factors in baboon placental syncytiotrophoblast. ENDOCRINOLOGY. 147:2986-2996.
Full Text via DOI: 10.1210/en.2005-0887 PMID: 16527850
2006

Suppression of extravillous trophoblast invasion of uterine spiral arteries by estrogen during early baboon pregnancy. PLACENTA. 27:483-490.
Full Text via DOI: 10.1016/j.placenta.2005.04.005 PMID: 15990167
2006

Regulation of baboon fetal ovarian folliculogenesis by estrogen. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 247:41-46.
Full Text via DOI: 10.1016/j.mce.2005.11.045 PMID: 16420971
2006

Developmental regulation of placental villous angiopoietin-1 and-2 expression during baboon pregnancy.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 108A-108A.
2006

Suppression of extravillous cytotrophoblast (EVT) invasion of uterine spiral arteries (UA) by estrogen during early primate pregnancy: Modulatory role of vascular endothelial growth factor (VEGF).. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 180A-180A.
2005

Development of a coculture system and use of confocal laser fluorescent microscopy to study human microvascular endothelial cell and mural cell interaction. MICROVASCULAR RESEARCH. 70:43-52.
Full Text via DOI: 10.1016/j.mvr.2005.04.008 PMID: 15967470
2005

Estrogen elicits cortical zone-specific effects on development of the primate fetal adrenal gland. ENDOCRINOLOGY. 146:1737-1744.
Full Text via DOI: 10.1210/en.2004-1124 PMID: 15618362
2005

Developmental regulation of growth of the primate fetal adrenal cortex by estrogen: Cell cycle regulators.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 239A-239A.
2005

Estrogen elicits cortical zone specific effects on development of the primate fetal adrenal gland.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 238A-239A.
2005

Longitudinal assessment of fetal growth and blood flow indices by Doppler ultrasonography during the second half of baboon pregnancy.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 155A-156A.
2005

Regulation of extravillous trophoblast invasion of uterine spiral arteries by estrogen during baboon pregnancy.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 298A-298A.
2004

Acute Temporal Regulation of Placental Vascular Endothelial Growth/Permeability Factor Expression in Baboons by Estrogen1. BIOLOGY OF REPRODUCTION. 71:1694-1698.
Full Text via DOI: 10.1095/biolreprod.104.030882 PMID: 15269101
2004

Estrogen Modulates Developmentally Regulated Gene Expression in the Fetal Baboon Liver. ENDOCRINE. 23:219-228.
Full Text via DOI: 10.1385/endo:23:2-3:219 PMID: 15146103
2004

Estrogen Suppression Induces Papillary Gingival Overgrowth in Pregnant Baboons. Journal of Periodontology. 75:693-701.
Full Text via DOI: 10.1902/jop.2004.75.5.693 PMID: 15212352
2004

Expression of Estrogen Receptors α and β in the Fetal Baboon Testisand Epididymis1. BIOLOGY OF REPRODUCTION. 70:1106-1113.
Full Text via DOI: 10.1095/biolreprod.103.022665 PMID: 15033877
2004

Localization and Developmental Expression of the Activin Signal Transduction Proteins Smads 2, 3, and 4 in the Baboon Fetal Ovary1. BIOLOGY OF REPRODUCTION. 70:586-592.
Full Text via DOI: 10.1095/biolreprod.103.018598 PMID: 14585818
2004

Regulation of Oocyte Microvilli Development in the Baboon Fetal Ovary by Estrogen. ENDOCRINOLOGY. 145:959-966.
Full Text via DOI: 10.1210/en.2003-1078 PMID: 14592953
2004

Regulation of Placental Vascular Endothelial Growth/Permeability Factor Expression and Angiogenesis by Estrogen during Early Baboon Pregnancy. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 89:5803-5809.
Full Text via DOI: 10.1210/jc.2004-0479 PMID: 15531545
2003

Acute Temporal Regulation of Vascular Endothelial Growth/Permeability Factor Expression and Endothelial Morphology in the Baboon Endometrium by Ovarian Steroids. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 88:2844-2852.
Full Text via DOI: 10.1210/jc.2002-021546 PMID: 12788898
2003

Developmental Regulation of Follicle-Stimulating Hormone Receptor Messenger RNA Expression in the Baboon Fetal Ovary1. BIOLOGY OF REPRODUCTION. 68:1911-1917.
Full Text via DOI: 10.1095/biolreprod.102.011494 PMID: 12606356
2003

Effect of Estrogen on Vascular Endothelial Growth/Permeability Factor Expression by Glandular Epithelial and Stromal Cells in the Baboon Endometrium1. BIOLOGY OF REPRODUCTION. 68:1997-2004.
Full Text via DOI: 10.1095/biolreprod.102.011288 PMID: 12606344
2003

Effect of estrogen on angiogenesis in co-cultures of human endometrial cells and microvascular endothelial cells. Human Reproduction. 18:2039-2047.
Full Text via DOI: 10.1093/humrep/deg415 PMID: 14507818
2003

Fetal Lung Maturation in Estrogen-Deprived Baboons. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 88:471-477.
Full Text via DOI: 10.1210/jc.2001-010228 PMID: 12519892
2003

Functional Differentiation of the Placental Syncytiotrophoblast: Effect of Estrogen on Chorionic Somatomammotropin Expression during Early Primate Pregnancy. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 88:4316-4323.
Full Text via DOI: 10.1210/jc.2002-022052 PMID: 12970304
2003

Steroid hormone regulation of angiogenesis in the primate endometrium. FRONTIERS IN BIOSCIENCE. d416-429.
Full Text via DOI: 10.2741/1001 PMID: 12456304
2003

Up-Regulation of α-Inhibin Expression in the Fetal Ovary of Estrogen-Suppressed Baboons Is Associated with Impaired Fetal Ovarian Folliculogenesis1. BIOLOGY OF REPRODUCTION. 68:1989-1996.
Full Text via DOI: 10.1095/biolreprod.102.011908 PMID: 12606324
2002

Developmental Regulation of Baboon Fetal Ovarian Maturation by Estrogen1. BIOLOGY OF REPRODUCTION. 67:1148-1156.
Full Text via DOI: 10.1095/biolreprod67.4.1148 PMID: 12297530
2002

Expression of Estrogen Receptors α and β in the Baboon Fetal Ovary1. BIOLOGY OF REPRODUCTION. 66:1054-1060.
Full Text via DOI: 10.1095/biolreprod66.4.1054 PMID: 11906925
2002

Expression of Vascular Endothelial Growth/Permeability Factor by Endometrial Glandular Epithelial and Stromal Cells in Baboons during the Menstrual Cycle and after Ovariectomy. ENDOCRINOLOGY. 143:4007-4017.
Full Text via DOI: 10.1210/en.2002-220385 PMID: 12239112
2001

Developmental Regulation of Morphological Differentiation of Placental Villous Trophoblast in the Baboon. PLACENTA. 22:276-283.
Full Text via DOI: 10.1053/plac.2000.0621 PMID: 11286563
2001

Developmental Regulation of Placental Insulin-Like Growth Factor (IGF)-II and IGF-Binding Protein-1 and -2 Messenger RNA Expression During Primate Pregnancy1. BIOLOGY OF REPRODUCTION. 65:1208-1214.
Full Text via DOI: 10.1095/biolreprod65.4.1208 PMID: 11566745
2001

Developmental Regulation of Vascular Endothelial Growth/Permeability Factor Messenger Ribonucleic Acid Levels in and Vascularization of the Villous Placenta During Baboon Pregnancy*. ENDOCRINOLOGY. 142:2050-2057.
Full Text via DOI: 10.1210/endo.142.5.8174
2001

Developmental maturation of primate placental trophoblast: placental cytosolic and secretory phospholipase A2 expression after estrogen suppression of baboons. PROSTAGLANDINS & OTHER LIPID MEDIATORS. 66:155-163.
Full Text via DOI: 10.1016/s0090-6980(01)00157-5 PMID: 11577780
2001

Estrogen Regulates 11β-Hydroxysteroid Dehydrogenase-1 and -2 Localization in Placental Syncytiotrophoblast in the Second Half of Primate Pregnancy. ENDOCRINOLOGY. 142:4496-4503.
Full Text via DOI: 10.1210/endo.142.10.8434
2001

Expression of the mRNAs and Proteins for the Na+/H+Exchangers and Their Regulatory Factors in Baboon and Human Placental Syncytiotrophoblast. ENDOCRINOLOGY. 142:3685-3692.
Full Text via DOI: 10.1210/endo.142.8.8343
2001

Localization and Developmental Regulation of 11β-Hydroxysteroid Dehydrogenase-1 and -2 in the Baboon Syncytiotrophoblast1. ENDOCRINOLOGY. 142:68-80.
Full Text via DOI: 10.1210/endo.142.1.7877
2000

The role of estrogen in the maintenance of primate pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 182:432-438.
Full Text via DOI: 10.1016/s0002-9378(00)70235-3 PMID: 10694348
1999

Central Integrative Role of Oestrogen in Modulating the Communication between the Placenta and Fetus that Results in Primate Fetal–placental Development. PLACENTA. 129-139.
Full Text via DOI: 10.1053/plac.1998.0359 PMID: 10195732
1999

Cloning of the 11β-hydroxysteroid dehydrogenase (11β-HSD)-2 gene in the baboon: effects of estradiol on promoter activity of 11β-HSD-1 and -2 in placental JEG-3 cells. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1444:101-110.
Full Text via DOI: 10.1016/s0167-4781(98)00248-6 PMID: 9931459
1999

Development of the Baboon Fetal Adrenal Gland: Regulation of the Ontogenesis of the Definitive and Transitional Zones by Adrenocorticotropin1. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 84:3831-3835.
Full Text via DOI: 10.1210/jcem.84.10.6058
1999

Developmental expression of and effect of betamethasone on the messenger ribonucleic acid levels for peptide growth factors in the baboon fetal adrenal gland. JOURNAL OF ENDOCRINOLOGY. 163:123-130.
Full Text via DOI: 10.1677/joe.0.1630123 PMID: 10495414
1999

Expression of the 11β-Hydroxysteroid Dehydrogenase Types 1 and 2 Proteins in Human and Baboon Placental Syncytiotrophoblast. PLACENTA. 20:575-582.
Full Text via DOI: 10.1053/plac.1999.0416 PMID: 10452912
1999

Functional Capacity of Fetal Zone Cells of the Baboon Fetal Adrenal Gland: A Major Source of α-Inhibin1. BIOLOGY OF REPRODUCTION. 61:142-146.
Full Text via DOI: 10.1095/biolreprod61.1.142 PMID: 10377042
1999

Identification and Developmental Expression of the Estrogen Receptor α and β in the Baboon Fetal Adrenal Gland1. ENDOCRINOLOGY. 140:5953-5961.
Full Text via DOI: 10.1210/endo.140.12.7182
1999

Regulation of functional differentiation of the placental villous syncytiotrophoblast by estrogen during primate pregnancy1. Steroids. 64:624-627.
Full Text via DOI: 10.1016/s0039-128x(99)00043-4 PMID: 10503719
1998

Analysis of apoptosis and expression of bcl-2 gene family members in the human and baboon ovary. Cell Death & Differentiation. 5:67-76.
Full Text via DOI: 10.1038/sj.cdd.4400316 PMID: 10200447
1998

Central integrative role of oestrogen in the regulation of placental steroidogenic maturation and the development of the fetal pituitary-adrenocortical axis in the baboon. HUMAN REPRODUCTION UPDATE. 4:406-419.
Full Text via DOI: 10.1093/humupd/4.4.406 PMID: 9825855
1998

Developmental Maturation of Baboon Placental Trophoblast: Expression of Messenger Ribonucleic Acid and Protein Levels of Cytosolic and Secretory Phospholipases A21. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 83:2861-2867.
Full Text via DOI: 10.1210/jcem.83.8.5019
1998

Effect of Maternal Betamethasone Administration at Midgestation on Baboon Fetal Adrenal Gland Development and Adrenocorticotropin Receptor Messenger Ribonucleic Acid Expression1. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 83:976-982.
Full Text via DOI: 10.1210/jcem.83.3.4638
1997

Cloning and expression of the 11β-hydroxysteroid dehydrogenase type 1 gene in the baboon1Note: This work was supported by NIH Research Grant R01 HD-13294.1. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 127:201-209.
Full Text via DOI: 10.1016/s0303-7207(97)04008-2 PMID: 9099915
1997

Decline in Adrenocorticotropin Receptor Messenger Ribonucleic Acid Expression in the Baboon Fetal Adrenocortical Zone in the Second Half of Pregnancy1. ENDOCRINOLOGY. 138:1634-1641.
Full Text via DOI: 10.1210/endo.138.4.5079
1997

Estrogen Regulation of Placental P-450 Cholesterol Side-Chain Cleavage Enzyme Messenger Ribonucleic Acid Levels and Activity During Baboon Pregnancy1. ENDOCRINOLOGY. 138:452-459.
Full Text via DOI: 10.1210/endo.138.1.4833
1997

Estrogen Stimulation of P450 Cholesterol Side-Chain Cleavage Activity in Cultures of Human Placental Syncytiotrophoblasts1. BIOLOGY OF REPRODUCTION. 56:272-278.
Full Text via DOI: 10.1095/biolreprod56.1.272 PMID: 9002660
1997

Functional Differentiation of Placental Syncytiotrophoblasts during Baboon Pregnancy: Developmental Expression of Chorionic Somatomammotropin Messenger Ribonucleic Acid and Protein Levels1. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 82:4105-4110.
Full Text via DOI: 10.1210/jcem.82.12.4453
1997

Immunocytochemical identification of the oestrogen receptor in the nuclei of cultured human placental syncytiotrophoblasts. PLACENTA. 18:365-370.
Full Text via DOI: 10.1016/s0143-4004(97)80071-9 PMID: 9179930
1997

Inhibition of Fetal Adrenal Adrenocorticotropin Receptor Messenger Ribonucleic Acid Expression by Betamethasone Administration to the Baboon Fetus in Late Gestation1. ENDOCRINOLOGY. 138:2705-2712.
Full Text via DOI: 10.1210/endo.138.7.5225
1996

Biphasic developmental expression of adrenocorticotropin receptor messenger ribonucleic acid levels in the baboon fetal adrenal gland.. ENDOCRINOLOGY. 137:1292-1298.
Full Text via DOI: 10.1210/endo.137.4.8625902
1996

Developmental expression of placental trophoblast P-450 cholesterolside-chain cleavage, adrenodoxin and Δ5-3β-Hydroxysteroid dehydrogenase/isomerase messenger ribonucleic acids during baboon pregnancy. PLACENTA. 17:595-602.
Full Text via DOI: 10.1016/s0143-4004(96)80077-4 PMID: 8916208
1996

Developmental increase in expression of the messenger ribonucleic acid and protein levels of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta.. ENDOCRINOLOGY. 137:5678-5684.
Full Text via DOI: 10.1210/endo.137.12.8940399
1996

Developmental regulation of corticosteroid-binding globulin biosynthesis in the baboon fetus.. ENDOCRINOLOGY. 137:3323-3328.
Full Text via DOI: 10.1210/endo.137.8.8754758
1996

Hypothalamic Corticotropin-Releasing Hormone Expression in the Baboon Fetus at Mid- and Late Gestation1. BIOLOGY OF REPRODUCTION. 55:559-566.
Full Text via DOI: 10.1095/biolreprod55.3.559 PMID: 8862772
1996

Interconversion of cortisol and cortisone in the baboon placenta at midgestation: Expression of 11β-hydroxysteroid dehydrogenase type 1 messenger RNA. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 58:403-410.
Full Text via DOI: 10.1016/0960-0760(96)00049-0 PMID: 8903424
1996

Progesterone and 20α-Hydroxypregn-4-En-3-One (20α-OHP) in the Pregnant Baboon: Selective Placental Secretion of 20α-OHP into the Fetal Compartment'1. BIOLOGY OF REPRODUCTION. 55:854-859.
Full Text via DOI: 10.1095/biolreprod55.4.854 PMID: 8879500
1996

Regulation of human placental trophoblast low-density lipoprotein uptake in vitro by estrogen.. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 81:2675-2679.
Full Text via DOI: 10.1210/jcem.81.7.8675596
1995

Actions of Placental and Fetal Adrenal Steroid Hormones in Primate Pregnancy*. ENDOCRINE REVIEWS. 16:608-648.
Full Text via DOI: 10.1210/edrv-16-5-608
1995

Activation of the Baboon Fetal Pituitary-Adrenocortical Axis at Midgestation by Estrogen: Responsivity of the Fetal Adrenal Gland to Adrenocorticotropic Hormone in Vitro1. BIOLOGY OF REPRODUCTION. 53:996-1002.
Full Text via DOI: 10.1095/biolreprod53.5.996 PMID: 8527531
1995

Developmental increase in low density lipoprotein receptor messenger ribonucleic acid levels in placental syncytiotrophoblasts during baboon pregnancy.. ENDOCRINOLOGY. 136:5540-5546.
Full Text via DOI: 10.1210/endo.136.12.7588306
1995

Suppression of maternal adrenal dehydroepiandrosterone and dehydroepiandrosterone sulfate production by estrogen during baboon pregnancy.. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 80:3201-3208.
Full Text via DOI: 10.1210/jcem.80.11.7593427
1994

Activation of the baboon fetal pituitary-adrenocortical axis at midgestation by estrogen: enhancement of fetal pituitary proopiomelanocortin messenger ribonucleic acid expression.. ENDOCRINOLOGY. 135:2581-2587.
Full Text via DOI: 10.1210/endo.135.6.7988446
1994

Influence of Fetectomy on Serum Pregnancy-Associated Plasma Protein-A Concentrations in the Baboon1. BIOLOGY OF REPRODUCTION. 50:442-448.
Full Text via DOI: 10.1095/biolreprod50.2.442 PMID: 7511420
1993

Developmental regulation of protein kinase-A and -C activities in the baboon fetal adrenal.. ENDOCRINOLOGY. 132:2491-2497.
Full Text via DOI: 10.1210/endo.132.6.8504752
1992

Developmental increase in placental low density lipoprotein uptake during baboon pregnancy.. ENDOCRINOLOGY. 130:1698-1706.
Full Text via DOI: 10.1210/endo.130.3.1537317
1992

Utilization of maternal and fetal androstenedione for placental estrogen production at mid and late baboon pregnancy. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 41:171-178.
Full Text via DOI: 10.1016/0960-0760(92)90045-k PMID: 1543685
1991

Activation of the Baboon Fetal Pituitary-Adrenocortical Axis at Midgestation by Estrogen: Adrenal Δ5-3β-Hydroxysteroid Dehydrogenase and 17α-Hydroxylase-17,20-Lyase Activity*. ENDOCRINOLOGY. 128:2395-2401.
Full Text via DOI: 10.1210/endo-128-5-2395 PMID: 2019257
1991

Influence of the Fetus and Estrogen on Maternal Serum Growth Hormone, Insulin-Like Growth Factor-II, and Epidermal Growth Factor Concentrations during Baboon Pregnancy*. ENDOCRINOLOGY. 129:3109-3117.
Full Text via DOI: 10.1210/endo-129-6-3109 PMID: 1954892
1991

Regulation of Placental Low Density Lipoprotein Uptake in Baboons by Estrogen*. ENDOCRINOLOGY. 128:450-458.
Full Text via DOI: 10.1210/endo-128-1-450 PMID: 1986938
1991

Regulation of Placental Low-Density Lipoprotein Uptake in Baboons by Estrogen: Dose-Dependent Effects of the Anti-Estrogen Ethamoxytriphetol (MER-25)1. BIOLOGY OF REPRODUCTION. 45:43-48.
Full Text via DOI: 10.1095/biolreprod45.1.43 PMID: 1878435
1991

Responsivity of the Baboon Fetal Pituitary to Corticotropin-Releasing Hormonein Uteroat Midgestation*. ENDOCRINOLOGY. 129:1424-1428.
Full Text via DOI: 10.1210/endo-129-3-1424 PMID: 1651849
1990

Activation of the Baboon Fetal Hypothalamic-Pituitary Adrenocortical Axis at Midgestation by Estrogen-Induced Changes in Placental Corticosteroid Metabolism*. ENDOCRINOLOGY. 127:3117-3123.
Full Text via DOI: 10.1210/endo-127-6-3117 PMID: 2249642
1990

Influence of the Fetus and Estrogen on Serum Concentrations and Placental Formation of Insulin-Like Growth Factor I during Baboon Pregnancy*. ENDOCRINOLOGY. 127:2400-2407.
Full Text via DOI: 10.1210/endo-127-5-2400 PMID: 2226324
1990

Interconversion of Cortisol and Cortisone in Baboon Trophoblast and Decidua Cells in Culture*. ENDOCRINOLOGY. 127:1735-1741.
Full Text via DOI: 10.1210/endo-127-4-1735 PMID: 2401233
1990

Modulation of Adrenocorticotropin-Stimulated Baboon Fetal Adrenal Dehydroepiandrosterone Formationin Vitroby Estrogen at Mid- and Late Gestation*. ENDOCRINOLOGY. 126:3083-3088.
Full Text via DOI: 10.1210/endo-126-6-3083 PMID: 2161746
1990

Placental Steroid Hormone Biosynthesis in Primate Pregnancy*. ENDOCRINE REVIEWS. 124-150.
Full Text via DOI: 10.1210/edrv-11-1-124 PMID: 2180685
1990

Regulation of 1lβ-Hydroxysteroid Dehydrogenase Activity in the Baboon Placenta by Estrogen*. ENDOCRINOLOGY. 126:2742-2748.
Full Text via DOI: 10.1210/endo-126-5-2742 PMID: 2328704
1990

Regulation of the Primate Fetal Adrenal Cortex*. ENDOCRINE REVIEWS. 151-176.
Full Text via DOI: 10.1210/edrv-11-1-151 PMID: 2180686
1989

Effect of Estrogen on Pituitary Peptide-Induced Dehydroepiandrosterone Secretion in the Baboon Fetus at Midgestation*. ENDOCRINOLOGY. 125:1519-1524.
Full Text via DOI: 10.1210/endo-125-3-1519 PMID: 2547589
1989

Regulation of Progesterone Biosynthesis by Estrogen during Baboon Pregnancy: Placental Mitochondrial Cholesterol Side-Chain Cleavage Activity in Antiestrogen (Ethamoxytriphetol, MER-25)-Treated Baboons*. ENDOCRINOLOGY. 124:1638-1645.
Full Text via DOI: 10.1210/endo-124-4-1638 PMID: 2924716
1989

The effect of estrogen on placental delivery after fetectomy in baboons. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 160:237-241.
Full Text via DOI: 10.1016/0002-9378(89)90128-2 PMID: 2912088
1988

Effect of Estrogen on the Metabolism of Cortisol and Cortisone in the Baboon Fetus at Midgestation1. BIOLOGY OF REPRODUCTION. 38:1006-1011.
Full Text via DOI: 10.1095/biolreprod38.5.1006 PMID: 3408768
1988

Effect of the Antiestrogen Ethamoxytriphetol (MER-25) on Placental Low Density Lipoprotein Uptake and Degradation in Baboons*. ENDOCRINOLOGY. 122:2019-2026.
Full Text via DOI: 10.1210/endo-122-5-2019 PMID: 3359975
1988

Metabolism of Cortisol and Cortisone in the Baboon Fetus at Midgestation*. ENDOCRINOLOGY. 122:84-88.
Full Text via DOI: 10.1210/endo-122-1-84 PMID: 3335216
1988

Regulation of Baboon Fetal Adrenal Androgen Formation by Pituitary Peptides at Mid- and Late Gestation*. ENDOCRINOLOGY. 122:546-551.
Full Text via DOI: 10.1210/endo-122-2-546 PMID: 2828002
1988

The Effects of Adrenocorticotropin and Prolactin on Adrenal Dehydroepiandrosterone Secretion in the Baboon Fetus*. ENDOCRINOLOGY. 122:646-650.
Full Text via DOI: 10.1210/endo-122-2-646 PMID: 2828008
1988

The Regulation of Transplacental Cortisol- Cortisone Metabolism by Estrogen in Pregnant Baboons*. ENDOCRINOLOGY. 122:78-83.
Full Text via DOI: 10.1210/endo-122-1-78 PMID: 3335215
1987

Changes in the Pattern of Androgen Formation in Vitro by the Baboon Fetal Adrenal Gland at Mid- and Late Gestation1. BIOLOGY OF REPRODUCTION. 37:1192-1197.
Full Text via DOI: 10.1095/biolreprod37.5.1192 PMID: 2964875
1987

Effect of estrogen on dehydroepiandrosterone formation by baboon fetal adrenal cells in vitro. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 156:1275-1278.
Full Text via DOI: 10.1016/0002-9378(87)90162-1 PMID: 3034061
1987

Effects of anesthetic agents on the adrenocortical system of female baboons. American Journal of Primatology. 325-332.
Full Text via DOI: 10.1002/ajp.1350130309 PMID: 31973468
1987

Fetal Regulation of Transplacental Cortisol-Cortisone Metabolism in the Baboon*. ENDOCRINOLOGY. 120:2529-2533.
Full Text via DOI: 10.1210/endo-120-6-2529 PMID: 3569142
1987

Transuterofetoplacental Conversion of Pregnenolone to Progesterone in Antiestrogen-Treated Baboons*. ENDOCRINOLOGY. 121:1265-1271.
Full Text via DOI: 10.1210/endo-121-4-1265 PMID: 3653027
1986

Regulation of Progesterone Formation by Human Placental Cells in Culture*. ENDOCRINOLOGY. 119:998-1003.
Full Text via DOI: 10.1210/endo-119-3-998 PMID: 2942394
1986

Testosterone Production by Collagenase-Dispersed Cells from Baboon Fetal Testis1. BIOLOGY OF REPRODUCTION. 35:372-376.
Full Text via DOI: 10.1095/biolreprod35.2.372 PMID: 3021248
1985

Prolactin Stimulates Adrenal Androgen Secretion in Infant Baboons*. ENDOCRINOLOGY. 117:1968-1973.
Full Text via DOI: 10.1210/endo-117-5-1968 PMID: 2995004
1985

Regulation of Baboon Fetal Adrenal Androgen Production by Adrenocorticotropic Hormone, Prolactin, and Growth Hormone1. BIOLOGY OF REPRODUCTION. 33:545-550.
Full Text via DOI: 10.1095/biolreprod33.3.545 PMID: 2996643
1985

THE PLACENTA REMAINS FUNCTIONAL FOLLOWING FETECTOMY IN BABOONS. ENDOCRINOLOGY. 843-845.
Full Text via DOI: 10.1210/endo-116-2-843 PMID: 3155680
1985

The effects of cortisone on the interconversion of cortisol and cortisone in the baboon. Journal of Steroid Biochemistry. 23:275-278.
Full Text via DOI: 10.1016/0022-4731(85)90405-4 PMID: 4046601
1984

Comparison of cortisol-cortisone interconversion in vitro by the human and baboon placenta. Steroids. 44:229-240.
Full Text via DOI: 10.1016/0039-128x(84)90004-7 PMID: 6598930
1984

Effect of the Antiestrogen Ethamoxytriphetol (MER-25) and Luteectomy on Serum Progesterone Concentrations in Pregnant Baboons*. ENDOCRINOLOGY. 115:1717-1721.
Full Text via DOI: 10.1210/endo-115-5-1717 PMID: 6489260
1984

Source and Regulation of 17α-Hydroxyprogesterone During Baboon Pregnancy. BIOLOGY OF REPRODUCTION. 31:471-479.
Full Text via DOI: 10.1095/biolreprod31.3.471 PMID: 6487691
1984

Transuteroplacental Metabolism of Cortisol and Cortisone during Mid- and Late Gestation in the Baboon*. ENDOCRINOLOGY. 115:1946-1951.
Full Text via DOI: 10.1210/endo-115-5-1946 PMID: 6489265
1982

The effects of estrogen on cortisol metabolism in female baboons. Steroids. 39:471-477.
Full Text via DOI: 10.1016/0039-128x(82)90048-4 PMID: 7147281
1981

Effect of maternal administration of the antiestrogen ethamoxy triphetol throughout the last third of baboon gestation upon neonatal corticoid production. Steroids. 37:45-50.
Full Text via DOI: 10.1016/0039-128x(81)90006-4 PMID: 7222142
1981

Luteal Function in Baboons with Administration of the Antiestrogen Ethamoxytriphetol (MER-25) Throughout the Luteal Phase of the Menstrual Cycle1. BIOLOGY OF REPRODUCTION. 25:451-457.
Full Text via DOI: 10.1095/biolreprod25.3.451 PMID: 7306635
1980

The Influence of Fetectomy at Midgestation upon the Serum Concentrations of Progesterone, Estrone, and Estradiol in Baboons. ENDOCRINOLOGY. 107:766-770.
Full Text via DOI: 10.1210/endo-107-3-766 PMID: 6772429
1980

The utilization of placental substrates for cortisol synthesis by the baboon fetus near term. Steroids. 35:591-597.
Full Text via DOI: 10.1016/s0039-128x(80)80011-0 PMID: 6771896
1977

Serum cortisol levels affect the metabolic clearance rate of progesterone in female baboons. Steroids. 30:561-568.
Full Text via DOI: 10.1016/0039-128x(77)90100-3 PMID: 415386

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