Lattanzio, Frank A.
- Retired, Physiological Sciences 2023 -
Contact Info
Overview
overview
-
Bibliography and training
University of Miami, Coral Gables, FL
BS 1971 Biology
University of Miami, Coral Gables, FL
MS 1981 Pharmacology
University of Miami, Coral Gables, FL
PhD 1984 Pharmacology
University of Texas Health Science Center,Dallas TX
Postdoc 1984-1986 CV and skeletal muscle biochemistry and pharmacology
2011-pres Director, EVMS Microscopy and Imaging Facility
2014-pres Director, T.R. Lee Center for Ocular Pharmacology, EVMS
2017-pres Professor, Department of Physiological Sciences, EVMS
Publications
selected publications
-
2019Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment. FRONTIERS IN ENDOCRINOLOGY. 10.Full Text via DOI: 10.3389/fendo.2019.00311 PMID: 31156558
-
2019Peptide Inhibitor of Complement C1 (PIC1) Inhibits Growth of Pathogenic Bacteria. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 25:83-92.Full Text via DOI: 10.1007/s10989-017-9651-z
-
2018Peptide inhibitor of complement C1 modulates transfusion related acute lung injury in a novel rat model. MOLECULAR IMMUNOLOGY. 177-177.Full Text via DOI: 10.1016/j.molimm.2018.06.129
-
2017Therapeutic hypothermia modulates complement factor C3a and C5a levels in a rat model of hypoxic ischemic encephalopathy. PEDIATRIC RESEARCH. 81:654-662.Full Text via DOI: 10.1038/pr.2016.271 PMID: 28002390
-
2017Learner Improvement From a Simulation-Enhanced Ultrasonography Curriculum for First-Year Medical Students. JOURNAL OF ULTRASOUND IN MEDICINE. 36:609-619.Full Text via DOI: 10.7863/ultra.15.12025 PMID: 28127792
-
2017Alterations in expression of endometrial milk fat globule-EGF factor 8 (MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis. JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA. 21:313-320.Full Text via DOI: 10.5935/1518-0557.20170056 PMID: 28967712
-
2016Peptide inhibitor of complement C1 modulates acute intravascular hemolysis of mismatched red blood cells in rats. TRANSFUSION. 56:2133-2145.Full Text via DOI: 10.1111/trf.13674 PMID: 27282513
-
2015Peptide Inhibitor of Complement significantly reduces brain injury in a rat model of neonatal hypoxic ischemic encephalopathy. MOLECULAR IMMUNOLOGY. 181-182.
-
2015Therapeutic hypothermia modulates C3a and C5a levels in a rat model of neonatal hypoxic ischemic encephalopathy. MOLECULAR IMMUNOLOGY. 181-181.
-
2015Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats. PLOS ONE. 10.Full Text via DOI: 10.1371/journal.pone.0132446 PMID: 26196285
-
2015Jellyfish Model for Ototoxicity. OTOLOGY & NEUROTOLOGY. 36:329-335.Full Text via DOI: 10.1097/MAO.0000000000000402 PMID: 24786541
-
2014Complement inhibition significantly decreases red blood cell lysis in a rat model of acute intravascular hemolysis. TRANSFUSION. 54:2892-2900.Full Text via DOI: 10.1111/trf.12695 PMID: 24806146
-
2014MINIMAL SYSTEMIC ABSORPTION AND ROBUST SAFETY PROFILE OF OC-10X, A VASCULAR DISRUPTING AGENT, AFTER TOPICAL APPLICATION IN NORMAL SUBJECTS. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.
-
2014Non-invasive measurement of brain temperature using radiometric thermometry: experimental validation and clinical observations in asphyxiated newborns.. Journal of neonatal-perinatal medicine. 279-86.Full Text via DOI: 10.3233/NPM-14814041 PMID: 25468621
-
2013Expression of eNOS and VEGF in Normoxia Mediated Vasculopathy in Rat Retinopathy of Prematurity Model. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.
-
2013A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility. MOLECULAR IMMUNOLOGY. 53:132-139.Full Text via DOI: 10.1016/j.molimm.2012.07.012 PMID: 22906481
-
2012Efficacy of a Phosphorodiamidate Morpholino Oligomer Antisense Compound in the Inhibition of Corneal Transplant Rejection in a Rat Cornea Transplant Model. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS. 28:194-201.Full Text via DOI: 10.1089/jop.2011.0135 PMID: 22149555
-
2012Accelerated Atherosclerosis in Apoe(-/-) Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 32:247-U172.Full Text via DOI: 10.1161/ATVBAHA.111.240358 PMID: 22199371
-
2011Lacritin, a Novel Human Tear Glycoprotein, Promotes Sustained Basal Tearing and Is Well Tolerated. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 52:6265-6270.Full Text via DOI: 10.1167/iovs.10-6220 PMID: 21087963
-
20103,4-Methylenedioxymethamphetamine Alters Left Ventricular Function and Activates Nuclear Factor-Kappa B (NF-kappa B) in a Time and Dose Dependent Manner. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 11:4843-4863.Full Text via DOI: 10.3390/ijms11124743 PMID: 21614177
-
2010Comparison of the Pharmacokinetics of WIN 55212-2 and Latanoprost in the Human Cornea Versus the Human Sclera. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.
-
2010The Terminal Regions of Lacritin May Contain Functional Domains That Increase Tear Flow. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.
-
2008Propylaminated Biotinylglycans: Useful Reagents for Glycobiological Investigations. GLYCOBIOLOGY. 983-983.
-
2008Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor-mediated mechanism of action. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS. 24:104-115.Full Text via DOI: 10.1089/jop.2007.0074 PMID: 18201139
-
2008Comparison of topical and intravenous administration of WIN 55-212-2 in normotensive rabbits. CURRENT EYE RESEARCH. 33:857-863.Full Text via DOI: 10.1080/02713680802419724 PMID: 18853319
-
2007Proteomic and fractal analysis of a phenotypic transition in the growth of human breast cells in culture. JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT.Full Text via DOI: 10.1088/1742-5468/2007/12/P12006
-
2007Analysis of protein-linked glycosylation in a sperm-somatic cell adhesion system. GLYCOBIOLOGY. 17:553-567.Full Text via DOI: 10.1093/glycob/cwm025 PMID: 17337520
-
2007Ocular pharmacokinetics and pharmacodynamics of synthetic cannabinoid, O-1812, in a perfused rat eye model. FASEB JOURNAL. A417-A417.
-
2006Primate granulosa cell response via prostaglandin E2 receptors increases late in the periovulatory interval. BIOLOGY OF REPRODUCTION. 75:868-876.Full Text via DOI: 10.1095/biolreprod.106.053769 PMID: 16943366
-
2006The expression of bisecting type N-glycans and ligands for DC-SIGN on human sperm. GLYCOBIOLOGY. 1161-1161.
-
2006Chronic topical administration of WIN-55-212-2 maintains a reduction in IOP in a rat glaucoma model without adverse effects. EXPERIMENTAL EYE RESEARCH. 82:753-759.Full Text via DOI: 10.1016/j.exer.2005.09.017 PMID: 16289049
-
2006
-
2006Novel endocannabinoids reduce intraocular pressure in a rat glaucoma model. FASEB JOURNAL. A682-A682.
-
2006Argon laser photodynamic therapy of human corneal neovascularization after intravenous administration of dihematoporphyrin ether. AMERICAN JOURNAL OF OPHTHALMOLOGY. 141:524-529.Full Text via DOI: 10.1016/j.ajo.2005.11.003 PMID: 16490500
-
2006Differential O-glycosylation of a conserved domain expressed in murine and human ZP3. BIOCHEMISTRY. 45:637-647.Full Text via DOI: 10.1021/bi0512804 PMID: 16401092
-
2005Cyclosporin as an adjunct to glaucoma filtration surgery. JOURNAL OF GLAUCOMA. 14:441-447.
-
2005Do injections of 5-fluorouracil after trabeculectomy have toxic effects on the anterior segment?. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS. 21:223-235.
-
2005
Research
research overview
- I have over thirty years of experience in pharmacology, physiology and toxicology and have been involved in developing and testing a number of drugs and devices using in vitro and in vivo models of drug distribution, inflammation and infection. Other research interests include the use of fluorescent indicator and other optical methods in detecting and monitoring normal and pathological changes in cells, tissues and preclinical models.
projects
-
Current Project
-
Past Project
Contact
preferred title
- Professor
full name
- Frank A. Lattanzio, PhD
visualizations
research areas
- Acoustics
- Biochemistry & Molecular Biology
- Cardiovascular System & Cardiology
- Cell Biology
- Chemistry
- Endocrinology & Metabolism
- Hematology
- Immunology
- Life Sciences & Biomedicine - Other Topics
- Mechanics
- Neurosciences & Neurology
- Obstetrics & Gynecology
- Ophthalmology
- Otorhinolaryngology
- Pediatrics
- Pharmacology & Pharmacy
- Physics
- Radiology, Nuclear Medicine & Medical Imaging
- Reproductive Biology
- Science & Technology - Other Topics